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Estimating and Correcting for Off-Target Cellular Contamination in Brain Cell Type Specific RNA-Seq Data

Transcriptionally profiling minor cellular populations remains an ongoing challenge in molecular genomics. Single-cell RNA sequencing has provided valuable insights into a number of hypotheses, but practical and analytical challenges have limited its widespread adoption. A similar approach, which we...

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Detalles Bibliográficos
Autores principales: Sicherman, Jordan, Newton, Dwight F., Pavlidis, Paul, Sibille, Etienne, Tripathy, Shreejoy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966716/
https://www.ncbi.nlm.nih.gov/pubmed/33746712
http://dx.doi.org/10.3389/fnmol.2021.637143