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Contrast enhanced X-ray computed tomography imaging of amyloid plaques in Alzheimer disease rat model on lab based micro CT system
Amyloid plaques are small (~ 50 μm), highly-dense aggregates of amyloid beta (Aβ) protein in brain tissue, supposed to play a key role in pathogenesis of Alzheimer’s disease (AD). Plaques´ in vivo detection, spatial distribution and quantitative characterization could be an essential marker in diagn...
Autores principales: | Kavkova, Michaela, Zikmund, Tomas, Kala, Annu, Salplachta, Jakub, Proskauer Pena, Stephanie L., Kaiser, Josef, Jezek, Karel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966753/ https://www.ncbi.nlm.nih.gov/pubmed/33727592 http://dx.doi.org/10.1038/s41598-021-84579-x |
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