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Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2
The adipose tissue is regarded as an endocrine organ and secretes bioactive adipokines modulating chronic inflammation and oxidative stress in obesity. Gal-9 is secreted out upon cell injuries, interacts with T-cell immunoglobulin-3 (Tim-3) and induces apoptosis in activated Th1 cells. Gal-9 also bi...
Autores principales: | Nunoue, Tomokazu, Yamaguchi, Satoshi, Teshigawara, Sanae, Katayama, Akihiro, Nakatsuka, Atsuko, Eguchi, Jun, Niki, Toshiro, Wada, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966757/ https://www.ncbi.nlm.nih.gov/pubmed/33727589 http://dx.doi.org/10.1038/s41598-021-85080-1 |
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