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Monocentric experience of primary hyperparathyroidism surgery in Algeria

INTRODUCTION: Primary hyperparathyroidism (PHPT) remains a relatively underdiagnosed disease in developing countries. The aim of this study was to assess the demographic, pathological, biochemical, and surgical characteristics of patients with primary hyperparathyroidism in a university hospital dep...

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Autor principal: Nouikes Zitouni, Souad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966862/
https://www.ncbi.nlm.nih.gov/pubmed/33748732
http://dx.doi.org/10.1016/j.sopen.2021.02.002
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author Nouikes Zitouni, Souad
author_facet Nouikes Zitouni, Souad
author_sort Nouikes Zitouni, Souad
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description INTRODUCTION: Primary hyperparathyroidism (PHPT) remains a relatively underdiagnosed disease in developing countries. The aim of this study was to assess the demographic, pathological, biochemical, and surgical characteristics of patients with primary hyperparathyroidism in a university hospital department of otolaryngology in eastern Algeria. MATERIALS AND METHOD: We performed a retrospective analysis of the records of 62 patients operated in our department for primary hyperparathyroidism between January 2002 and December 2013. RESULTS: The mean age was 47.7 ± 15 years with a female preponderance (88.7%). The mode of discovery was during a biological assessment for bone syndrome in 42% of cases. The mean calcemia was 2.92 ± 0.6 mmol/L, and the intact serum parathyroid hormone was 867.78 ± 954.50 pmol/L. A total of 54.8% of patients had bilateral neck exploration, and 45.2% had minimally invasive open parathyroidectomy. Postoperative complications were dominated by severe hypocalcemia and hungry bone syndrome. CONCLUSION: The diagnosis of primary hyperparathyroidism in our country is late, and management is often performed after the appearance of bone and renal complications.
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spelling pubmed-79668622021-03-19 Monocentric experience of primary hyperparathyroidism surgery in Algeria Nouikes Zitouni, Souad Surg Open Sci Article INTRODUCTION: Primary hyperparathyroidism (PHPT) remains a relatively underdiagnosed disease in developing countries. The aim of this study was to assess the demographic, pathological, biochemical, and surgical characteristics of patients with primary hyperparathyroidism in a university hospital department of otolaryngology in eastern Algeria. MATERIALS AND METHOD: We performed a retrospective analysis of the records of 62 patients operated in our department for primary hyperparathyroidism between January 2002 and December 2013. RESULTS: The mean age was 47.7 ± 15 years with a female preponderance (88.7%). The mode of discovery was during a biological assessment for bone syndrome in 42% of cases. The mean calcemia was 2.92 ± 0.6 mmol/L, and the intact serum parathyroid hormone was 867.78 ± 954.50 pmol/L. A total of 54.8% of patients had bilateral neck exploration, and 45.2% had minimally invasive open parathyroidectomy. Postoperative complications were dominated by severe hypocalcemia and hungry bone syndrome. CONCLUSION: The diagnosis of primary hyperparathyroidism in our country is late, and management is often performed after the appearance of bone and renal complications. Elsevier 2021-02-10 /pmc/articles/PMC7966862/ /pubmed/33748732 http://dx.doi.org/10.1016/j.sopen.2021.02.002 Text en © 2021 The Author http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Nouikes Zitouni, Souad
Monocentric experience of primary hyperparathyroidism surgery in Algeria
title Monocentric experience of primary hyperparathyroidism surgery in Algeria
title_full Monocentric experience of primary hyperparathyroidism surgery in Algeria
title_fullStr Monocentric experience of primary hyperparathyroidism surgery in Algeria
title_full_unstemmed Monocentric experience of primary hyperparathyroidism surgery in Algeria
title_short Monocentric experience of primary hyperparathyroidism surgery in Algeria
title_sort monocentric experience of primary hyperparathyroidism surgery in algeria
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966862/
https://www.ncbi.nlm.nih.gov/pubmed/33748732
http://dx.doi.org/10.1016/j.sopen.2021.02.002
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