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The methyltransferase PRMT1 regulates γ-globin translation

Induction of fetal hemoglobin to overcome adult β-globin gene deficiency is an effective therapeutic strategy to ameliorate human β-hemoglobinopathies. Previous work has revealed that fetal γ-globin can be translationally induced via integrated stress signaling, but other studies have indicated that...

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Detalles Bibliográficos
Autores principales:	Wang, Ying, Li, Xinyu, Ge, Jingru, Liu, Ming, Pang, Xiaming, Liu, Jianpeng, Luo, Cheng, Xu, Yichen, Zhao, Quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966866/ https://www.ncbi.nlm.nih.gov/pubmed/33587951 http://dx.doi.org/10.1016/j.jbc.2021.100417

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