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A Review of Leishmaniasis: Current Knowledge and Future Directions

PURPOSE OF REVIEW: The goal of this review is to summarize the current knowledge of the epidemiology, clinical manifestations, diagnosis, and treatment of cutaneous, mucosal, and visceral leishmaniasis. We will describe the most recent findings and suggest areas of further research in the leishmania...

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Autores principales: Mann, Sarah, Frasca, Katherine, Scherrer, Sara, Henao-Martínez, Andrés F., Newman, Sabrina, Ramanan, Poornima, Suarez, José A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966913/
https://www.ncbi.nlm.nih.gov/pubmed/33747716
http://dx.doi.org/10.1007/s40475-021-00232-7
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author Mann, Sarah
Frasca, Katherine
Scherrer, Sara
Henao-Martínez, Andrés F.
Newman, Sabrina
Ramanan, Poornima
Suarez, José A
author_facet Mann, Sarah
Frasca, Katherine
Scherrer, Sara
Henao-Martínez, Andrés F.
Newman, Sabrina
Ramanan, Poornima
Suarez, José A
author_sort Mann, Sarah
collection PubMed
description PURPOSE OF REVIEW: The goal of this review is to summarize the current knowledge of the epidemiology, clinical manifestations, diagnosis, and treatment of cutaneous, mucosal, and visceral leishmaniasis. We will describe the most recent findings and suggest areas of further research in the leishmaniasis field. RECENT FINDINGS: This article reviews newer leishmaniasis tests (including rapid diagnostic tests using rK39 antibodies), vaccine candidates, and updated treatment recommendations. SUMMARY: While leishmaniasis is a complex disease, learning the prominent clinical manifestations and major parasite species can guide the recommendations for diagnosis and treatment.
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spelling pubmed-79669132021-03-17 A Review of Leishmaniasis: Current Knowledge and Future Directions Mann, Sarah Frasca, Katherine Scherrer, Sara Henao-Martínez, Andrés F. Newman, Sabrina Ramanan, Poornima Suarez, José A Curr Trop Med Rep Skin and Soft Tissue Infections in Returning Travelers from the Tropics (C Franco-Paredes, Section Editor) PURPOSE OF REVIEW: The goal of this review is to summarize the current knowledge of the epidemiology, clinical manifestations, diagnosis, and treatment of cutaneous, mucosal, and visceral leishmaniasis. We will describe the most recent findings and suggest areas of further research in the leishmaniasis field. RECENT FINDINGS: This article reviews newer leishmaniasis tests (including rapid diagnostic tests using rK39 antibodies), vaccine candidates, and updated treatment recommendations. SUMMARY: While leishmaniasis is a complex disease, learning the prominent clinical manifestations and major parasite species can guide the recommendations for diagnosis and treatment. Springer International Publishing 2021-03-17 2021 /pmc/articles/PMC7966913/ /pubmed/33747716 http://dx.doi.org/10.1007/s40475-021-00232-7 Text en © The Author(s), under exclusive licence to Springer Nature Switzerland AG part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Skin and Soft Tissue Infections in Returning Travelers from the Tropics (C Franco-Paredes, Section Editor)
Mann, Sarah
Frasca, Katherine
Scherrer, Sara
Henao-Martínez, Andrés F.
Newman, Sabrina
Ramanan, Poornima
Suarez, José A
A Review of Leishmaniasis: Current Knowledge and Future Directions
title A Review of Leishmaniasis: Current Knowledge and Future Directions
title_full A Review of Leishmaniasis: Current Knowledge and Future Directions
title_fullStr A Review of Leishmaniasis: Current Knowledge and Future Directions
title_full_unstemmed A Review of Leishmaniasis: Current Knowledge and Future Directions
title_short A Review of Leishmaniasis: Current Knowledge and Future Directions
title_sort review of leishmaniasis: current knowledge and future directions
topic Skin and Soft Tissue Infections in Returning Travelers from the Tropics (C Franco-Paredes, Section Editor)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7966913/
https://www.ncbi.nlm.nih.gov/pubmed/33747716
http://dx.doi.org/10.1007/s40475-021-00232-7
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