Development of a High-Throughput Screening Assay to Identify Inhibitors of the SARS-CoV-2 Guanine-N7-Methyltransferase Using RapidFire Mass Spectrometry

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) represents a significant threat to human health. Despite its similarity to related coronaviruses, there are currently no specific treatments for COVID-19 infection, and therefore there is an urgent need to develop therapies for this and fu...

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Detalles Bibliográficos
Autores principales: Pearson, Lesley-Anne, Green, Charlotte J., Lin, De, Petit, Alain-Pierre, Gray, David W., Cowling, Victoria H., Fordyce, Euan A.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Laboratory Automation and Screening. Published by Elsevier Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967019/
https://www.ncbi.nlm.nih.gov/pubmed/33724070
http://dx.doi.org/10.1177/24725552211000652

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