Exosomal miR-155 from M1-polarized macrophages promotes EndoMT and impairs mitochondrial function via activating NF-κB signaling pathway in vascular endothelial cells after traumatic spinal cord injury

Pathologically, blood-spinal-cord-barrier (BSCB) disruption after spinal cord injury (SCI) leads to infiltration of numerous peripheral macrophages into injured areas and accumulation around newborn vessels. Among the leaked macrophages, M1-polarized macrophages are dominant and play a crucial role...

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Detalles Bibliográficos
Autores principales: Ge, Xuhui, Tang, Pengyu, Rong, Yuluo, Jiang, Dongdong, Lu, Xiao, Ji, Chengyue, Wang, Jiaxing, Huang, Chenyu, Duan, Ao, Liu, Yang, Chen, Xinglin, Chen, Xichen, Xu, Zhiyang, Wang, Feng, Wang, Zibin, Li, Xiaoyan, Zhao, Wene, Fan, Jin, Liu, Wei, Yin, Guoyong, Cai, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967037/
https://www.ncbi.nlm.nih.gov/pubmed/33714739
http://dx.doi.org/10.1016/j.redox.2021.101932

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