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Hairpin‐Spacer crRNA‐Enhanced CRISPR/Cas13a System Promotes the Specificity of Single Nucleotide Polymorphism (SNP) Identification
The Cas13a system has great potential in RNA interference and molecular diagnostic fields. However, lacking guidelines for crRNA design hinders practical applications of the Cas13a system in RNA editing and single nucleotide polymorphism identification. This study posits that crRNAs with hairpin spa...
Autores principales: | Ke, Yuqing, Huang, Shiyi, Ghalandari, Behafarid, Li, Sijie, Warden, Antony R., Dang, Jingqi, Kang, Lin, Zhang, Yu, Wang, Yunqing, Sun, Yiqing, Wang, Jinglin, Cui, Daxiang, Zhi, Xiao, Ding, Xianting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967054/ https://www.ncbi.nlm.nih.gov/pubmed/33747742 http://dx.doi.org/10.1002/advs.202003611 |
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