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Genetic stabilization by p53 involves growth regulatory and repair pathways

p53 performs a plethora of activities, which are directed towards the maintenance of the genomic integrity and constitute its universal role as a tumor suppressor. 1000 to 10000 latent p53 molecules are permanently available in order to monitor DNA exchange processes in mitotically growing cells. Af...

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Detalles Bibliográficos
Autor principal: Wiesmüller, Lisa
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC79672/
https://www.ncbi.nlm.nih.gov/pubmed/12488620
http://dx.doi.org/10.1155/S1110724301000043