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Cellular senescence: ex vivo p53-dependent asymmetric cell kinetics
Although senescence is a defining property of euploid mammalian cells, its physiologic basis remains obscure. Previously, cell kinetics properties of normal tissue cells have not been considered in models for senescence. We now provide evidence that senescence is in fact the natural consequence of n...
Autores principales: | Rambhatla, Lakshmi, Bohn, Shirley A, Stadler, Patrizia B, Boyd, Jonathan T, Coss, Ronald A, Sherley, James L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC79675/ https://www.ncbi.nlm.nih.gov/pubmed/12488624 http://dx.doi.org/10.1155/S1110724301000079 |
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