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The Impact of Depression Symptoms in Patients with Parkinson’s Disease: A Novel Case-Control Investigation

Parkinson’s disease is a common neurodegenerative disease and it is known to cause motor disturbances associated with musculoskeletal problems of the locomotor apparatus, and non-motor symptoms, that are believed to have a harmful effect on health, social functioning and mobility. The aim of this st...

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Autores principales: Jiménez-Cebrián, Ana María, Becerro-de-Bengoa-Vallejo, Ricardo, Losa-Iglesias, Marta Elena, López-López, Daniel, Calvo-Lobo, César, Palomo-López, Patricia, Romero-Morales, Carlos, Navarro-Flores, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967746/
https://www.ncbi.nlm.nih.gov/pubmed/33804349
http://dx.doi.org/10.3390/ijerph18052369
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author Jiménez-Cebrián, Ana María
Becerro-de-Bengoa-Vallejo, Ricardo
Losa-Iglesias, Marta Elena
López-López, Daniel
Calvo-Lobo, César
Palomo-López, Patricia
Romero-Morales, Carlos
Navarro-Flores, Emmanuel
author_facet Jiménez-Cebrián, Ana María
Becerro-de-Bengoa-Vallejo, Ricardo
Losa-Iglesias, Marta Elena
López-López, Daniel
Calvo-Lobo, César
Palomo-López, Patricia
Romero-Morales, Carlos
Navarro-Flores, Emmanuel
author_sort Jiménez-Cebrián, Ana María
collection PubMed
description Parkinson’s disease is a common neurodegenerative disease and it is known to cause motor disturbances associated with musculoskeletal problems of the locomotor apparatus, and non-motor symptoms, that are believed to have a harmful effect on health, social functioning and mobility. The aim of this study was to evaluate depression in patients with Parkinson’s Disease (PD) compared to subjects who do not have it. The sample consisted of 124 participants (mean age 69.18 ± 9.12). Patients with PD were recruited from a center of excellence for Parkinson’s disease (cases n = 62) and healthy subjects without PD from their relatives and caregivers (control n = 62). The Spanish version of Beck’s Depression Inventory (BDI) scores and categories were collected. A clear statistically significant difference (p < 0.05) was evident in the BDI scores between both groups. Parkinson’s patients presented worse results on the BDI = 15.48 ± 7.24 points compared to healthy subjects with BDI = 7.03 ± 6.99 points. Regarding BDI categories, there were statistically significant differences (p < 0.001) for the greater BDI categories in the Parkinson’s group compared with healthy subjects. The depression represents an important potential risk for increased symptoms and negative impact among patients with PD compared with healthy subjects.
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spelling pubmed-79677462021-03-18 The Impact of Depression Symptoms in Patients with Parkinson’s Disease: A Novel Case-Control Investigation Jiménez-Cebrián, Ana María Becerro-de-Bengoa-Vallejo, Ricardo Losa-Iglesias, Marta Elena López-López, Daniel Calvo-Lobo, César Palomo-López, Patricia Romero-Morales, Carlos Navarro-Flores, Emmanuel Int J Environ Res Public Health Article Parkinson’s disease is a common neurodegenerative disease and it is known to cause motor disturbances associated with musculoskeletal problems of the locomotor apparatus, and non-motor symptoms, that are believed to have a harmful effect on health, social functioning and mobility. The aim of this study was to evaluate depression in patients with Parkinson’s Disease (PD) compared to subjects who do not have it. The sample consisted of 124 participants (mean age 69.18 ± 9.12). Patients with PD were recruited from a center of excellence for Parkinson’s disease (cases n = 62) and healthy subjects without PD from their relatives and caregivers (control n = 62). The Spanish version of Beck’s Depression Inventory (BDI) scores and categories were collected. A clear statistically significant difference (p < 0.05) was evident in the BDI scores between both groups. Parkinson’s patients presented worse results on the BDI = 15.48 ± 7.24 points compared to healthy subjects with BDI = 7.03 ± 6.99 points. Regarding BDI categories, there were statistically significant differences (p < 0.001) for the greater BDI categories in the Parkinson’s group compared with healthy subjects. The depression represents an important potential risk for increased symptoms and negative impact among patients with PD compared with healthy subjects. MDPI 2021-03-01 /pmc/articles/PMC7967746/ /pubmed/33804349 http://dx.doi.org/10.3390/ijerph18052369 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Jiménez-Cebrián, Ana María
Becerro-de-Bengoa-Vallejo, Ricardo
Losa-Iglesias, Marta Elena
López-López, Daniel
Calvo-Lobo, César
Palomo-López, Patricia
Romero-Morales, Carlos
Navarro-Flores, Emmanuel
The Impact of Depression Symptoms in Patients with Parkinson’s Disease: A Novel Case-Control Investigation
title The Impact of Depression Symptoms in Patients with Parkinson’s Disease: A Novel Case-Control Investigation
title_full The Impact of Depression Symptoms in Patients with Parkinson’s Disease: A Novel Case-Control Investigation
title_fullStr The Impact of Depression Symptoms in Patients with Parkinson’s Disease: A Novel Case-Control Investigation
title_full_unstemmed The Impact of Depression Symptoms in Patients with Parkinson’s Disease: A Novel Case-Control Investigation
title_short The Impact of Depression Symptoms in Patients with Parkinson’s Disease: A Novel Case-Control Investigation
title_sort impact of depression symptoms in patients with parkinson’s disease: a novel case-control investigation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967746/
https://www.ncbi.nlm.nih.gov/pubmed/33804349
http://dx.doi.org/10.3390/ijerph18052369
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