Cargando…
The Impact of Depression Symptoms in Patients with Parkinson’s Disease: A Novel Case-Control Investigation
Parkinson’s disease is a common neurodegenerative disease and it is known to cause motor disturbances associated with musculoskeletal problems of the locomotor apparatus, and non-motor symptoms, that are believed to have a harmful effect on health, social functioning and mobility. The aim of this st...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967746/ https://www.ncbi.nlm.nih.gov/pubmed/33804349 http://dx.doi.org/10.3390/ijerph18052369 |
_version_ | 1783665946741702656 |
---|---|
author | Jiménez-Cebrián, Ana María Becerro-de-Bengoa-Vallejo, Ricardo Losa-Iglesias, Marta Elena López-López, Daniel Calvo-Lobo, César Palomo-López, Patricia Romero-Morales, Carlos Navarro-Flores, Emmanuel |
author_facet | Jiménez-Cebrián, Ana María Becerro-de-Bengoa-Vallejo, Ricardo Losa-Iglesias, Marta Elena López-López, Daniel Calvo-Lobo, César Palomo-López, Patricia Romero-Morales, Carlos Navarro-Flores, Emmanuel |
author_sort | Jiménez-Cebrián, Ana María |
collection | PubMed |
description | Parkinson’s disease is a common neurodegenerative disease and it is known to cause motor disturbances associated with musculoskeletal problems of the locomotor apparatus, and non-motor symptoms, that are believed to have a harmful effect on health, social functioning and mobility. The aim of this study was to evaluate depression in patients with Parkinson’s Disease (PD) compared to subjects who do not have it. The sample consisted of 124 participants (mean age 69.18 ± 9.12). Patients with PD were recruited from a center of excellence for Parkinson’s disease (cases n = 62) and healthy subjects without PD from their relatives and caregivers (control n = 62). The Spanish version of Beck’s Depression Inventory (BDI) scores and categories were collected. A clear statistically significant difference (p < 0.05) was evident in the BDI scores between both groups. Parkinson’s patients presented worse results on the BDI = 15.48 ± 7.24 points compared to healthy subjects with BDI = 7.03 ± 6.99 points. Regarding BDI categories, there were statistically significant differences (p < 0.001) for the greater BDI categories in the Parkinson’s group compared with healthy subjects. The depression represents an important potential risk for increased symptoms and negative impact among patients with PD compared with healthy subjects. |
format | Online Article Text |
id | pubmed-7967746 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-79677462021-03-18 The Impact of Depression Symptoms in Patients with Parkinson’s Disease: A Novel Case-Control Investigation Jiménez-Cebrián, Ana María Becerro-de-Bengoa-Vallejo, Ricardo Losa-Iglesias, Marta Elena López-López, Daniel Calvo-Lobo, César Palomo-López, Patricia Romero-Morales, Carlos Navarro-Flores, Emmanuel Int J Environ Res Public Health Article Parkinson’s disease is a common neurodegenerative disease and it is known to cause motor disturbances associated with musculoskeletal problems of the locomotor apparatus, and non-motor symptoms, that are believed to have a harmful effect on health, social functioning and mobility. The aim of this study was to evaluate depression in patients with Parkinson’s Disease (PD) compared to subjects who do not have it. The sample consisted of 124 participants (mean age 69.18 ± 9.12). Patients with PD were recruited from a center of excellence for Parkinson’s disease (cases n = 62) and healthy subjects without PD from their relatives and caregivers (control n = 62). The Spanish version of Beck’s Depression Inventory (BDI) scores and categories were collected. A clear statistically significant difference (p < 0.05) was evident in the BDI scores between both groups. Parkinson’s patients presented worse results on the BDI = 15.48 ± 7.24 points compared to healthy subjects with BDI = 7.03 ± 6.99 points. Regarding BDI categories, there were statistically significant differences (p < 0.001) for the greater BDI categories in the Parkinson’s group compared with healthy subjects. The depression represents an important potential risk for increased symptoms and negative impact among patients with PD compared with healthy subjects. MDPI 2021-03-01 /pmc/articles/PMC7967746/ /pubmed/33804349 http://dx.doi.org/10.3390/ijerph18052369 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Jiménez-Cebrián, Ana María Becerro-de-Bengoa-Vallejo, Ricardo Losa-Iglesias, Marta Elena López-López, Daniel Calvo-Lobo, César Palomo-López, Patricia Romero-Morales, Carlos Navarro-Flores, Emmanuel The Impact of Depression Symptoms in Patients with Parkinson’s Disease: A Novel Case-Control Investigation |
title | The Impact of Depression Symptoms in Patients with Parkinson’s Disease: A Novel Case-Control Investigation |
title_full | The Impact of Depression Symptoms in Patients with Parkinson’s Disease: A Novel Case-Control Investigation |
title_fullStr | The Impact of Depression Symptoms in Patients with Parkinson’s Disease: A Novel Case-Control Investigation |
title_full_unstemmed | The Impact of Depression Symptoms in Patients with Parkinson’s Disease: A Novel Case-Control Investigation |
title_short | The Impact of Depression Symptoms in Patients with Parkinson’s Disease: A Novel Case-Control Investigation |
title_sort | impact of depression symptoms in patients with parkinson’s disease: a novel case-control investigation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967746/ https://www.ncbi.nlm.nih.gov/pubmed/33804349 http://dx.doi.org/10.3390/ijerph18052369 |
work_keys_str_mv | AT jimenezcebriananamaria theimpactofdepressionsymptomsinpatientswithparkinsonsdiseaseanovelcasecontrolinvestigation AT becerrodebengoavallejoricardo theimpactofdepressionsymptomsinpatientswithparkinsonsdiseaseanovelcasecontrolinvestigation AT losaiglesiasmartaelena theimpactofdepressionsymptomsinpatientswithparkinsonsdiseaseanovelcasecontrolinvestigation AT lopezlopezdaniel theimpactofdepressionsymptomsinpatientswithparkinsonsdiseaseanovelcasecontrolinvestigation AT calvolobocesar theimpactofdepressionsymptomsinpatientswithparkinsonsdiseaseanovelcasecontrolinvestigation AT palomolopezpatricia theimpactofdepressionsymptomsinpatientswithparkinsonsdiseaseanovelcasecontrolinvestigation AT romeromoralescarlos theimpactofdepressionsymptomsinpatientswithparkinsonsdiseaseanovelcasecontrolinvestigation AT navarrofloresemmanuel theimpactofdepressionsymptomsinpatientswithparkinsonsdiseaseanovelcasecontrolinvestigation AT jimenezcebriananamaria impactofdepressionsymptomsinpatientswithparkinsonsdiseaseanovelcasecontrolinvestigation AT becerrodebengoavallejoricardo impactofdepressionsymptomsinpatientswithparkinsonsdiseaseanovelcasecontrolinvestigation AT losaiglesiasmartaelena impactofdepressionsymptomsinpatientswithparkinsonsdiseaseanovelcasecontrolinvestigation AT lopezlopezdaniel impactofdepressionsymptomsinpatientswithparkinsonsdiseaseanovelcasecontrolinvestigation AT calvolobocesar impactofdepressionsymptomsinpatientswithparkinsonsdiseaseanovelcasecontrolinvestigation AT palomolopezpatricia impactofdepressionsymptomsinpatientswithparkinsonsdiseaseanovelcasecontrolinvestigation AT romeromoralescarlos impactofdepressionsymptomsinpatientswithparkinsonsdiseaseanovelcasecontrolinvestigation AT navarrofloresemmanuel impactofdepressionsymptomsinpatientswithparkinsonsdiseaseanovelcasecontrolinvestigation |