Cargando…

miR-23a-3p regulates the proliferation and apoptosis of human lens epithelial cells by targeting Bcl-2 in an in vitro model of cataracts

Cataracts account for ~50% of the cases of blindness in individuals worldwide. The apoptosis of lens epithelial cells (LECs) occurs during the formation of cataracts, which is a non-congenital condition. Numerous microRNAs (miRs) have been reported to regulate apoptosis in LECs. For instance, miR-23...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yao, Pengxiang, Jiang, Jian, Ma, Xiaoping, Chen, Zhenzhong, Hong, Yufang, Wu, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7967796/ https://www.ncbi.nlm.nih.gov/pubmed/33777189 http://dx.doi.org/10.3892/etm.2021.9853

Ejemplares similares

miR-15a-3p affects the proliferation, migration and apoptosis of lens epithelial cells
por: Liu, Shu-Jun, et al.
Publicado: (2019)

miR-378a-5p and miR-630 induce lens epithelial cell apoptosis in cataract via suppression of E2F3
por: Gao, Weiwei, et al.
Publicado: (2020)

miR-24-p53 pathway evoked by oxidative stress promotes lens epithelial cell apoptosis in age-related cataracts
por: Lu, Bo, et al.
Publicado: (2018)

Rs1894720 polymorphism is associated with the risk of age-related cataract by regulating the proliferation of epithelial cells in the lens via the signalling pathway of MIAT/miR-26b/BCL2L2
por: Li, Yan, et al.
Publicado: (2020)

N(6)-Methyladenosine METTL3 Modulates the Proliferation and Apoptosis of Lens Epithelial Cells in Diabetic Cataract
por: Yang, Jun, et al.
Publicado: (2020)

SP1‐mediated lncRNA PVT1 modulates the proliferation and apoptosis of lens epithelial cells in diabetic cataract via miR‐214‐3p/MMP2 axis
por: Yang, Jun, et al.
Publicado: (2019)

miR-342-3p Regulates the Proliferation and Apoptosis of NSCLC Cells by Targeting BCL-2
por: Chen, Zhongjie, et al.
Publicado: (2021)

miR-34a suppresses proliferation and induces apoptosis of human lens epithelial cells by targeting E2F3
por: Xiang, Wu, et al.
Publicado: (2016)

MiR-4328 inhibits proliferation, metastasis and induces apoptosis in keloid fibroblasts by targeting BCL2 expression
por: Tang, Hongmei, et al.
Publicado: (2020)

lncRNA TUG1 regulates Smac/DIABLO expression by competitively inhibiting miR-29b and modulates the apoptosis of lens epithelial cells in age-related cataracts
por: Sun, Miaomiao, et al.
Publicado: (2023)

miR-143 and miR-145 disrupt the cervical epithelial barrier through dysregulation of cell adhesion, apoptosis and proliferation
por: Anton, Lauren, et al.
Publicado: (2017)

MiR-133b regulates bladder cancer cell proliferation and apoptosis by targeting Bcl-w and Akt1
por: Chen, Xiao-nan, et al.
Publicado: (2014)

miR-127 Regulates Cell Proliferation and Senescence by Targeting BCL6
por: Chen, Jingwen, et al.
Publicado: (2013)

Down-Regulation of MicroRNA-133b Suppresses Apoptosis of Lens Epithelial Cell by Up-Regulating BCL2L2 in Age-Related Cataracts
por: Zhang, Feng, et al.
Publicado: (2016)

Effects of microRNA-211 on proliferation and apoptosis of lens epithelial cells by targeting SIRT1 gene in diabetic cataract mice
por: Zeng, Kun, et al.
Publicado: (2017)

Expression of miR-181a and TGF-β2 in lens epithelial cells of patients with cataractous retinal detachment and its clinical significance
por: Jiang, Yanyun, et al.
Publicado: (2019)

MiR-34a-3p alters proliferation and apoptosis of meningioma cells in vitro and is directly targeting SMAD4, FRAT1 and BCL2
por: Werner, Tamara V., et al.
Publicado: (2017)

Exosome-delivered miR-153 from Trichinella spiralis promotes apoptosis of intestinal epithelial cells by downregulating Bcl2
por: Wang, Ruibiao, et al.
Publicado: (2023)

NEAT1 regulates cell proliferation and apoptosis of ovarian cancer by miR-34a-5p/BCL2
por: Ding, Nan, et al.
Publicado: (2017)

Astaxanthin inhibits proliferation and induces apoptosis of LX-2 cells by regulating the miR-29b/Bcl-2 pathway
por: Zhu, Shanshan, et al.
Publicado: (2019)

miR-424-5p regulates apoptosis and cell proliferation via targeting Bcl2 in nucleus pulposus cells
por: Lu, Hua-tuo, et al.
Publicado: (2020)

MIR34A modulates lens epithelial cell apoptosis and cataract development via the HK1/caspase 3 signaling pathway
por: Feng, Lujia, et al.
Publicado: (2023)

Radiation-Induced Alterations in Proliferation, Migration, and Adhesion in Lens Epithelial Cells and Implications for Cataract Development
por: Vigneux, Graysen, et al.
Publicado: (2022)

Expression of miR-664 and miR-184 on proliferation, apoptosis and migration of osteosarcoma cells
por: Tao, Pengfei, et al.
Publicado: (2019)

LINC01087 inhibits glioma cell proliferation and migration, and increases cell apoptosis via miR-384/Bcl-2 axis
por: Tian, Yao-Hui, et al.
Publicado: (2021)

Metformin promotes proliferation and suppresses apoptosis in Ox-LDL stimulated macrophages by regulating the miR-34a/Bcl2 axis
por: Feng, Liuliu, et al.
Publicado: (2019)

LncRNA PVT1 induces apoptosis and inflammatory response of bronchial epithelial cells by regulating miR-30b-5p/BCL2L11 axis in COPD
por: Fu, Taoli, et al.
Publicado: (2023)

miR‐15b enhances the proliferation and migration of lung adenocarcinoma by targeting BCL2
por: Wang, Jun, et al.
Publicado: (2020)

MiR‐486 promotes proliferation and suppresses apoptosis in myeloid cells by targeting Cebpa in vitro
por: Jiang, Jingwei, et al.
Publicado: (2018)

miR-326 Targets Antiapoptotic Bcl-xL and Mediates Apoptosis in Human Platelets
por: Yu, Shifang, et al.
Publicado: (2015)

miR-365 induces hepatocellular carcinoma cell apoptosis through targeting Bcl-2
por: Li, Mingfei, et al.
Publicado: (2017)

Entropic Imaging of Cataract Lens: An In Vitro Study
por: Zhou, Zhuhuang, et al.
Publicado: (2014)

miR-145 suppresses the proliferation, invasion and migration of NSCLC cells by regulating the BAX/BCL-2 ratio and the caspase-3 cascade
por: Pan, Yi, et al.
Publicado: (2018)

Orai3 exacerbates apoptosis of lens epithelial cells by disrupting Ca(2+) homeostasis in diabetic cataract
por: Wang, Yong, et al.
Publicado: (2021)

miR-10a inhibits cell proliferation and promotes cell apoptosis by targeting BCL6 in diffuse large B-cell lymphoma
por: Fan, Qian, et al.
Publicado: (2016)

Trichostatin A-induced miR-30a-5p regulates apoptosis and proliferation of keloid fibroblasts via targeting BCL2
por: Jian, Xiaoqing, et al.
Publicado: (2019)

miR-185-5p response to usnic acid suppresses proliferation and regulating apoptosis in breast cancer cell by targeting Bcl2
por: Değerli, Elif, et al.
Publicado: (2020)

The polyamidoamine-mediated inhibition of bcl-2 by small hairpin RNA to induce apoptosis in human lens epithelial cells
por: Wu, Xin-Hua, et al.
Publicado: (2012)

IGF-1 Promotes Epithelial-Mesenchymal Transition of Lens Epithelial Cells That Is Conferred by miR-3666 Loss
por: Wang, Chao, et al.
Publicado: (2022)

ALKBH5 inhibited autophagy of epithelial ovarian cancer through miR-7 and BCL-2
por: Zhu, Hongtao, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_cvrtha8pp7hns2niennr67i79a