Cargando…

Controversial roles of hepatocyte nuclear receptor 4 α on tumorigenesis

Hepatocyte nuclear receptor 4 α (HNF4α) is known to be a master transcription regulator of gene expression in multiple biological processes, particularly in liver development and liver function. To date, the function of HNF4α in human cancers has been widely investigated; however, the critical roles...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zhu, Zhang, Ying, Zhang, Jianwen, Deng, Qiong, Liang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968000/ https://www.ncbi.nlm.nih.gov/pubmed/33747213 http://dx.doi.org/10.3892/ol.2021.12617

Ejemplares similares

The role of hepatocyte nuclear factor 4α (HNF4α) in tumorigenesis
por: Sang, Lei, et al.
Publicado: (2022)

The role of the orphan nuclear receptor COUP-TFII in tumorigenesis
por: Xu, Mafei, et al.
Publicado: (2015)

Hepatocyte Nuclear Factor 4α (HNF4α) Plays a Controlling Role in Expression of the Retinoic Acid Receptor β (RARβ) Gene in Hepatocytes
por: Zolfaghari, Reza, et al.
Publicado: (2023)

Controversies Surrounding the Origin of Hepatocytes in Adult Livers and the in Vitro Generation or Propagation of Hepatocytes
por: Pek, Nicole Min Qian, et al.
Publicado: (2020)

Hepatocyte nuclear factor 4α in the pathogenesis of non-alcoholic fatty liver disease
por: Pan, Xiaoli, et al.
Publicado: (2022)

The nuclear receptor hepatocyte nuclear factor 4α acts as a morphogen to induce the formation of microvilli
por: Chiba, Hideki, et al.
Publicado: (2006)

H19 Is Expressed in Hybrid Hepatocyte Nuclear Factor 4α(+) Periportal Hepatocytes but Not Cytokeratin 19(+) Cholangiocytes in Cholestatic Livers
por: Jiang, YanChao, et al.
Publicado: (2018)

Role of hepatocyte nuclear factor 4-alpha in gastrointestinal and liver diseases
por: Yeh, Matthew M, et al.
Publicado: (2019)

Crystallization of hepatocyte nuclear factor 4α (HNF4α) in complex with the HNF1α promoter element
por: Lu, Peng, et al.
Publicado: (2008)

The impact of hepatocyte nuclear factor-1α on liver malignancies and cell stemness with metabolic consequences
por: Wang, Xue, et al.
Publicado: (2019)

Hepatocyte Nuclear Factor 4α Controls Iron Metabolism and Regulates Transferrin Receptor 2 in Mouse Liver
por: Matsuo, Shunsuke, et al.
Publicado: (2015)

Feedback loop between hepatocyte nuclear factor 1α and endoplasmic reticulum stress mitigates liver injury by downregulating hepatocyte apoptosis
por: Liu, Si-Ying, et al.
Publicado: (2022)

Placenta Accreta Spectrum Diagnosis Challenges and Controversies in Current Obstetrics: A Review
por: Arakaza, Arcade, et al.
Publicado: (2023)

Cancer genes and cancer stem cells in tumorigenesis: Evolutionary deep homology and controversies
por: Niculescu, Vladimir F.
Publicado: (2022)

The Role of the Eph Receptor Family in Tumorigenesis
por: Anderton, Meg, et al.
Publicado: (2021)

Developmental Regulation of Hepatitis B Virus Biosynthesis by Hepatocyte Nuclear Factor 4α
por: Li, Lie, et al.
Publicado: (2009)

Expression profile analysis of the inflammatory response regulated by hepatocyte nuclear factor 4α
por: Wang, Zhongyan, et al.
Publicado: (2011)

Hepatocyte nuclear factor 4α regulates megalin expression in proximal tubular cells
por: Sasaki, Shota, et al.
Publicado: (2018)

Apoptosis signal-regulating kinase 1 mediates the inhibitory effect of hepatocyte nuclear factor-4α on hepatocellular carcinoma
por: Jiang, Cai-Feng, et al.
Publicado: (2016)

Sirtuin 2 Prevents Liver Steatosis and Metabolic Disorders by Deacetylation of Hepatocyte Nuclear Factor 4α
por: Ren, Huihui, et al.
Publicado: (2021)

Hepatocyte nuclear factor 4α and cancer-related cell signaling pathways: a promising insight into cancer treatment
por: Lv, Duo-Duo, et al.
Publicado: (2021)

HIF-1α signaling: Essential roles in tumorigenesis and implications in targeted therapies
por: Zhao, Yan, et al.
Publicado: (2023)

SAT-162 Hepatocyte Nuclear Factor-4α (HNF44α) as a Target to Treat DM
por: Jorge dos Santos, Gustavo, et al.
Publicado: (2019)

The Role of Steroid Hormone Receptors in Urothelial Tumorigenesis
por: Ide, Hiroki, et al.
Publicado: (2020)

Proteomic Analysis of Native Hepatocyte Nuclear Factor-4α (HNF4α) Isoforms, Phosphorylation Status, and Interactive Cofactors
por: Daigo, Kenji, et al.
Publicado: (2011)

A review on hepatocyte nuclear factor-1beta and tumor
por: Yu, Dan-Dan, et al.
Publicado: (2015)

Localization of hepatocyte nuclear factor‐4α in the nucleolus and nucleus is regulated by its C‐terminus
por: Ogata, Makiko, et al.
Publicado: (2012)

Vesicle-Associated Membrane Protein-Associated Protein A Is Involved in Androgen Receptor Trafficking in Mouse Sertoli Cells
por: Deng, Qiong, et al.
Publicado: (2018)

The Controversial Role of Adiponectin in Appetite Regulation of Animals
por: Tang, Ni, et al.
Publicado: (2021)

Biophysical characterization of α-synuclein and its controversial structure
por: Alderson, T Reid, et al.
Publicado: (2013)

Generation of functional hepatocytes by forward programming with nuclear receptors
por: Tomaz, Rute A, et al.
Publicado: (2022)

Expression and localization of P1 promoter-driven hepatocyte nuclear factor-4α (HNF4α) isoforms in human and rats
por: Jiang, Shuying, et al.
Publicado: (2003)

Recent advances on the mechanisms of kidney stone formation (Review)
por: Wang, Zhu, et al.
Publicado: (2021)

Role of DKK4 in Tumorigenesis and Tumor Progression
por: Cai, Xinjia, et al.
Publicado: (2018)

Role of ACTN4 in Tumorigenesis, Metastasis, and EMT
por: Tentler, Dmitri, et al.
Publicado: (2019)

Emerging Insights into Liver X Receptor α in the Tumorigenesis and Therapeutics of Human Cancers
por: Han, Ning, et al.
Publicado: (2023)

Disruption of Tumor Suppressors HNF4α/HNF1α Causes Tumorigenesis in Liver
por: Teeli, Aamir Salam, et al.
Publicado: (2021)

Hepatocyte Growth Factor Overexpression Slows the Progression of 4NQO-Induced Oral Tumorigenesis
por: He, Xiaoxi, et al.
Publicado: (2021)

Role of hepatocyte nuclear factor 4 alpha in cell proliferation and gemcitabine resistance in pancreatic adenocarcinoma
por: Sun, Qiqing, et al.
Publicado: (2019)

Controversies in the Management of Endometrial Carcinoma
por: Zhang, Ying, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_js28v2ta0estc3b0v0dcpshp77