Retrospective serosurveillance for anti-SARS-CoV-2 immunoglobulin during a time of low prevalence: A cautionary tale

We performed a retrospective screening of 428 serum samples for anti-SARS-CoV-2  immunoglobulin during a period of low prevalence. Employing two different serological tests yielded discrepant results for 10 samples; highlighting an increased risk of potential  false positive results and the need for...

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Detalles Bibliográficos
Autores principales: Bird, Paul William, Holmes, Christopher, Fletcher, Oliver, Badhwar, Vinay, Toovey, Oliver, Tang, Julian Wei-Tze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd on behalf of The British Infection Association. 2021
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968146/
https://www.ncbi.nlm.nih.gov/pubmed/33744303
http://dx.doi.org/10.1016/j.jinf.2021.03.007
Descripción
Sumario:We performed a retrospective screening of 428 serum samples for anti-SARS-CoV-2  immunoglobulin during a period of low prevalence. Employing two different serological tests yielded discrepant results for 10 samples; highlighting an increased risk of potential  false positive results and the need for further confirmatory testing before publication of data.

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