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The Bdkrb2 gene family provides a novel view of viviparity adaptation in Sebastes schlegelii
BACKGROUND: Black rockfish (Sebastes schlegelii) is a viviparous teleost. We proposed that the rockfish ovarian wall had a similar function to the uterus of mammals previously. In the present study, the well-developed vascular system was observed in the ovarian wall and the exterior surface of the e...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968187/ https://www.ncbi.nlm.nih.gov/pubmed/33731008 http://dx.doi.org/10.1186/s12862-021-01774-0 |
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author | Niu, Jingjing Song, Weihao Li, Rui Yu, Haiyang Guan, Jian Qi, Jie He, Yan |
author_facet | Niu, Jingjing Song, Weihao Li, Rui Yu, Haiyang Guan, Jian Qi, Jie He, Yan |
author_sort | Niu, Jingjing |
collection | PubMed |
description | BACKGROUND: Black rockfish (Sebastes schlegelii) is a viviparous teleost. We proposed that the rockfish ovarian wall had a similar function to the uterus of mammals previously. In the present study, the well-developed vascular system was observed in the ovarian wall and the exterior surface of the egg membrane. In gestation, adaptation of the ovary vasculature to the rising needs of the embryos occurs through both vasodilation and neovascularization. Bdkrb2, encoding a receptor for bradykinin, plays a critical role in the control of vasodilatation by regulating nitric oxide production. RESULTS: Eight Bdkrb2 genes were identified in the black rockfish genome. These genes were located on chromosome 14, which are arranged in a tandem array, forming a gene cluster spanning 50 kb. Protein structure prediction, phylogenetic analysis, and transcriptome analysis showed that eight Bdkrb2 genes evolved two kinds of protein structure and three types of tissue expression pattern. Overexpression of two Bdkrb2 genes in zebrafish indicated a role of them in blood vessel formation or remodeling, which is an important procedure for the viviparous rockfish getting prepared for fertilization and embryos implantation. CONCLUSIONS: Our study characterizes eight Bdrkb2 genes in the black rockfish, which may contribute to preparation for fertilization and embryo implantation. This research provides a novel view of viviparity adaptation and lays the groundwork for future research into vascular regulation of ovarian tissue in the breeding cycle in black rockfish. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12862-021-01774-0. |
format | Online Article Text |
id | pubmed-7968187 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-79681872021-03-22 The Bdkrb2 gene family provides a novel view of viviparity adaptation in Sebastes schlegelii Niu, Jingjing Song, Weihao Li, Rui Yu, Haiyang Guan, Jian Qi, Jie He, Yan BMC Ecol Evol Research Article BACKGROUND: Black rockfish (Sebastes schlegelii) is a viviparous teleost. We proposed that the rockfish ovarian wall had a similar function to the uterus of mammals previously. In the present study, the well-developed vascular system was observed in the ovarian wall and the exterior surface of the egg membrane. In gestation, adaptation of the ovary vasculature to the rising needs of the embryos occurs through both vasodilation and neovascularization. Bdkrb2, encoding a receptor for bradykinin, plays a critical role in the control of vasodilatation by regulating nitric oxide production. RESULTS: Eight Bdkrb2 genes were identified in the black rockfish genome. These genes were located on chromosome 14, which are arranged in a tandem array, forming a gene cluster spanning 50 kb. Protein structure prediction, phylogenetic analysis, and transcriptome analysis showed that eight Bdkrb2 genes evolved two kinds of protein structure and three types of tissue expression pattern. Overexpression of two Bdkrb2 genes in zebrafish indicated a role of them in blood vessel formation or remodeling, which is an important procedure for the viviparous rockfish getting prepared for fertilization and embryos implantation. CONCLUSIONS: Our study characterizes eight Bdrkb2 genes in the black rockfish, which may contribute to preparation for fertilization and embryo implantation. This research provides a novel view of viviparity adaptation and lays the groundwork for future research into vascular regulation of ovarian tissue in the breeding cycle in black rockfish. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12862-021-01774-0. BioMed Central 2021-03-17 /pmc/articles/PMC7968187/ /pubmed/33731008 http://dx.doi.org/10.1186/s12862-021-01774-0 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Niu, Jingjing Song, Weihao Li, Rui Yu, Haiyang Guan, Jian Qi, Jie He, Yan The Bdkrb2 gene family provides a novel view of viviparity adaptation in Sebastes schlegelii |
title | The Bdkrb2 gene family provides a novel view of viviparity adaptation in Sebastes schlegelii |
title_full | The Bdkrb2 gene family provides a novel view of viviparity adaptation in Sebastes schlegelii |
title_fullStr | The Bdkrb2 gene family provides a novel view of viviparity adaptation in Sebastes schlegelii |
title_full_unstemmed | The Bdkrb2 gene family provides a novel view of viviparity adaptation in Sebastes schlegelii |
title_short | The Bdkrb2 gene family provides a novel view of viviparity adaptation in Sebastes schlegelii |
title_sort | bdkrb2 gene family provides a novel view of viviparity adaptation in sebastes schlegelii |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968187/ https://www.ncbi.nlm.nih.gov/pubmed/33731008 http://dx.doi.org/10.1186/s12862-021-01774-0 |
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