Cargando…
Overproduction of docosahexaenoic acid in Schizochytrium sp. through genetic engineering of oxidative stress defense pathways
BACKGROUND: Oxidation and peroxidation of lipids in microorganisms result in increased levels of intracellular reactive oxygen species (ROS) and reactive aldehydes, and consequent reduction of cell growth and lipid accumulation. RESULTS: To reduce oxygen-mediated cell damage and increase lipid and d...
Autores principales: | Han, Xiao, Li, Zhaohui, Wen, Ying, Chen, Zhi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968238/ https://www.ncbi.nlm.nih.gov/pubmed/33726826 http://dx.doi.org/10.1186/s13068-021-01918-w |
Ejemplares similares
-
Metabolic engineering to enhance biosynthesis of both docosahexaenoic acid and odd-chain fatty acids in Schizochytrium sp. S31
por: Wang, Fangzhong, et al.
Publicado: (2019) -
Enhancing docosahexaenoic acid production of Schizochytrium sp. by optimizing fermentation using central composite design
por: Ding, Jun, et al.
Publicado: (2022) -
Enhancement of docosahexaenoic acid production by overexpression of ATP-citrate lyase and acetyl-CoA carboxylase in Schizochytrium sp.
por: Han, Xiao, et al.
Publicado: (2020) -
Transcriptome and gene expression analysis of docosahexaenoic acid producer Schizochytrium sp. under different oxygen supply conditions
por: Bi, Zhi-Qian, et al.
Publicado: (2018) -
Improved production of docosahexaenoic acid in batch fermentation by newly-isolated strains of Schizochytrium sp. and Thraustochytriidae sp. through bioprocess optimization
por: Wang, Qiuzhen, et al.
Publicado: (2018)