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Acute dorsal myelopathy resulting from intramedullary cysticercus: a case report

BACKGROUND: Neurocysticercosis is the most common parasitic infection of the central nervous system, brain being the most frequent site. Intramedullary location of cysticercus is a rarely described entity in literature. Widespread dissemination of cysticercus is also considered a rare occurrence, an...

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Autores principales: Lahiri, Durjoy, Chowdhury, Abhishek, Dubey, Souvik, Ray, Biman Kanti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968257/
https://www.ncbi.nlm.nih.gov/pubmed/33726808
http://dx.doi.org/10.1186/s13256-021-02693-w
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author Lahiri, Durjoy
Chowdhury, Abhishek
Dubey, Souvik
Ray, Biman Kanti
author_facet Lahiri, Durjoy
Chowdhury, Abhishek
Dubey, Souvik
Ray, Biman Kanti
author_sort Lahiri, Durjoy
collection PubMed
description BACKGROUND: Neurocysticercosis is the most common parasitic infection of the central nervous system, brain being the most frequent site. Intramedullary location of cysticercus is a rarely described entity in literature. Widespread dissemination of cysticercus is also considered a rare occurrence, and only a handful of cases are documented, almost exclusively from tropical nations. Here we present a case of disseminated cysticercosis with rare initial presentation as acute dorsal myelopathy resulting from intramedullary cysticercus. CASE PRESENTATION: A 62-year-old male patient from India (Asian) presented with features of dorsal myelopathy as manifested by acute-onset symmetric paraparesis, sensory loss below umbilicus, and double sphincter dysfunction. General physical examination revealed pea-sized nodules in skin and tongue. On spinal cord imaging, it was found that he had intramedullary cysticercus with diffuse perilesional edema. Brain and muscle imaging showed extensive cysticercosis suggestive of dissemination. Histological examination from skin nodule and antibody assay confirmed the diagnosis of cysticercosis. Following steroid administration, our patient showed improvement with observable increase in power of the lower limbs. He was subsequently discharged with antiepileptics, symptomatic therapy, and regular physiotherapy. Antihelminthic agents were initially avoided in view of extensive cysticercosis in brain including crucial areas such as brainstem. CONCLUSION: Rare manifestation of a rare but treatable disorder makes it an important reportable observation in the context of tropical medicine.
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spelling pubmed-79682572021-03-22 Acute dorsal myelopathy resulting from intramedullary cysticercus: a case report Lahiri, Durjoy Chowdhury, Abhishek Dubey, Souvik Ray, Biman Kanti J Med Case Rep Case Report BACKGROUND: Neurocysticercosis is the most common parasitic infection of the central nervous system, brain being the most frequent site. Intramedullary location of cysticercus is a rarely described entity in literature. Widespread dissemination of cysticercus is also considered a rare occurrence, and only a handful of cases are documented, almost exclusively from tropical nations. Here we present a case of disseminated cysticercosis with rare initial presentation as acute dorsal myelopathy resulting from intramedullary cysticercus. CASE PRESENTATION: A 62-year-old male patient from India (Asian) presented with features of dorsal myelopathy as manifested by acute-onset symmetric paraparesis, sensory loss below umbilicus, and double sphincter dysfunction. General physical examination revealed pea-sized nodules in skin and tongue. On spinal cord imaging, it was found that he had intramedullary cysticercus with diffuse perilesional edema. Brain and muscle imaging showed extensive cysticercosis suggestive of dissemination. Histological examination from skin nodule and antibody assay confirmed the diagnosis of cysticercosis. Following steroid administration, our patient showed improvement with observable increase in power of the lower limbs. He was subsequently discharged with antiepileptics, symptomatic therapy, and regular physiotherapy. Antihelminthic agents were initially avoided in view of extensive cysticercosis in brain including crucial areas such as brainstem. CONCLUSION: Rare manifestation of a rare but treatable disorder makes it an important reportable observation in the context of tropical medicine. BioMed Central 2021-03-17 /pmc/articles/PMC7968257/ /pubmed/33726808 http://dx.doi.org/10.1186/s13256-021-02693-w Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Lahiri, Durjoy
Chowdhury, Abhishek
Dubey, Souvik
Ray, Biman Kanti
Acute dorsal myelopathy resulting from intramedullary cysticercus: a case report
title Acute dorsal myelopathy resulting from intramedullary cysticercus: a case report
title_full Acute dorsal myelopathy resulting from intramedullary cysticercus: a case report
title_fullStr Acute dorsal myelopathy resulting from intramedullary cysticercus: a case report
title_full_unstemmed Acute dorsal myelopathy resulting from intramedullary cysticercus: a case report
title_short Acute dorsal myelopathy resulting from intramedullary cysticercus: a case report
title_sort acute dorsal myelopathy resulting from intramedullary cysticercus: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968257/
https://www.ncbi.nlm.nih.gov/pubmed/33726808
http://dx.doi.org/10.1186/s13256-021-02693-w
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