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TMEM119 facilitates ovarian cancer cell proliferation, invasion, and migration via the PDGFRB/PI3K/AKT signaling pathway

BACKGROUND: Ovarian cancer (OV) is the deadliest gynecological cancer. Transmembrane protein 119 (TMEM119) has been reported as oncogene in several human cancers. However, the function of TMEM119 in OV is still poorly known. METHODS: Western blot and qRT-PCR were used to analyze TMEM119 levels. Tran...

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Detalles Bibliográficos
Autores principales: Sun, Tianshui, Bi, Fangfang, Liu, Zhuonan, Yang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968362/
https://www.ncbi.nlm.nih.gov/pubmed/33731124
http://dx.doi.org/10.1186/s12967-021-02781-x