Combined genomic and proteomic approaches reveal DNA binding sites and interaction partners of TBX2 in the developing lung

BACKGROUND: Tbx2 encodes a transcriptional repressor implicated in the development of numerous organs in mouse. During lung development TBX2 maintains the proliferation of mesenchymal progenitors, and hence, epithelial proliferation and branching morphogenesis. The pro-proliferative function was tra...

Descripción completa

Detalles Bibliográficos
Autores principales: Lüdtke, Timo H., Wojahn, Irina, Kleppa, Marc-Jens, Schierstaedt, Jasper, Christoffels, Vincent M., Künzler, Patrick, Kispert, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968368/
https://www.ncbi.nlm.nih.gov/pubmed/33731112
http://dx.doi.org/10.1186/s12931-021-01679-y

Ejemplares similares

Ejemplares similares