A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation

We report a case of coronavirus disease 2019 (COVID-19) after haploidentical transplantation with acute graft-versus-host disease (aGVHD). COVID-19 and aGVHD were improved under treatment with arbidol, remdesivir, methylprednisolone, and ruxolitinib. However, eventually, the patient died of septic s...

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Detalles Bibliográficos
Autores principales: Han, Dan, Sun, Yuqian, Xie, Rong, Zhu, Xiaojian, Zhong, Zhaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968447/
https://www.ncbi.nlm.nih.gov/pubmed/33815852
http://dx.doi.org/10.1155/2021/8878803
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author Han, Dan
Sun, Yuqian
Xie, Rong
Zhu, Xiaojian
Zhong, Zhaodong
author_facet Han, Dan
Sun, Yuqian
Xie, Rong
Zhu, Xiaojian
Zhong, Zhaodong
author_sort Han, Dan
collection PubMed
description We report a case of coronavirus disease 2019 (COVID-19) after haploidentical transplantation with acute graft-versus-host disease (aGVHD). COVID-19 and aGVHD were improved under treatment with arbidol, remdesivir, methylprednisolone, and ruxolitinib. However, eventually, the patient died of septic shock and multiple organ failure. It was concluded that the disease condition of this COVID-19 patient after transplantation was serious, complex, and variable, with poor prognosis.
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spelling pubmed-79684472021-04-02 A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation Han, Dan Sun, Yuqian Xie, Rong Zhu, Xiaojian Zhong, Zhaodong Case Rep Hematol Case Report We report a case of coronavirus disease 2019 (COVID-19) after haploidentical transplantation with acute graft-versus-host disease (aGVHD). COVID-19 and aGVHD were improved under treatment with arbidol, remdesivir, methylprednisolone, and ruxolitinib. However, eventually, the patient died of septic shock and multiple organ failure. It was concluded that the disease condition of this COVID-19 patient after transplantation was serious, complex, and variable, with poor prognosis. Hindawi 2021-03-17 /pmc/articles/PMC7968447/ /pubmed/33815852 http://dx.doi.org/10.1155/2021/8878803 Text en Copyright © 2021 Dan Han et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Han, Dan
Sun, Yuqian
Xie, Rong
Zhu, Xiaojian
Zhong, Zhaodong
A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation
title A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation
title_full A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation
title_fullStr A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation
title_full_unstemmed A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation
title_short A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation
title_sort case of severe covid-19 in a patient with acute graft-versus-host disease after haploidentical transplantation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968447/
https://www.ncbi.nlm.nih.gov/pubmed/33815852
http://dx.doi.org/10.1155/2021/8878803
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