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Counteracting Poisoning with Chemical Warfare Nerve Agents

Phosphylation of the pivotal enzyme acetylcholinesterase (AChE) by nerve agents (NAs) leads to irreversible inhibition of the enzyme and accumulation of neurotransmitter acetylcholine, which induces cholinergic crisis, that is, overstimulation of muscarinic and nicotinic membrane receptors in the ce...

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Detalles Bibliográficos
Autores principales: Hrvat, Nikolina Maček, Kovarik, Zrinka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968514/
https://www.ncbi.nlm.nih.gov/pubmed/33410774
http://dx.doi.org/10.2478/aiht-2020-71-3459