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A novel quantitative analysis method for idiopathic epiretinal membrane
PURPOSE: To introduce a novel method to quantitively analyse in three dimensions traction forces in a vast area of the ocular posterior pole. METHODS: Retrospective analysis of 14 eyes who underwent peeling surgery for idiopathic, symptomatic and progressive epiretinal membrane. The technique measur...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968655/ https://www.ncbi.nlm.nih.gov/pubmed/33730020 http://dx.doi.org/10.1371/journal.pone.0247192 |
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author | Allegrini, Davide Montesano, Giovanni Marconi, Stefania Rosso, Nicoletta Ometto, Giovanni Raimondi, Raffaele Auricchio, Ferdinando Tsoutsanis, Panagiotis Semeraro, Francesco Cacciatori, Matteo Crabb, David P. Romano, Mario R. |
author_facet | Allegrini, Davide Montesano, Giovanni Marconi, Stefania Rosso, Nicoletta Ometto, Giovanni Raimondi, Raffaele Auricchio, Ferdinando Tsoutsanis, Panagiotis Semeraro, Francesco Cacciatori, Matteo Crabb, David P. Romano, Mario R. |
author_sort | Allegrini, Davide |
collection | PubMed |
description | PURPOSE: To introduce a novel method to quantitively analyse in three dimensions traction forces in a vast area of the ocular posterior pole. METHODS: Retrospective analysis of 14 eyes who underwent peeling surgery for idiopathic, symptomatic and progressive epiretinal membrane. The technique measures the shift in position of vascular crossings after surgery from a fixed point, which is the retinal pigmented epithelium. This shift is defined as the relaxation index (RI) and represents a measure of the postoperative movement of the retina due to released traction after surgery. RESULTS: Best-corrected visual acuity was significantly better than baseline at all follow ups while the RI had its maximum value at baseline. Moreover, we found a significant correlation between best-corrected visual acuity at 6 months and RI at baseline. CONCLUSION: While all previous published methods focused on bi-dimensional changes observed in a small region, this study introduces a three-dimensional assessment of tractional forces. Future integration of RI into built-in processing software will allow systematic three-dimensional measurement of intraretinal traction. |
format | Online Article Text |
id | pubmed-7968655 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-79686552021-03-31 A novel quantitative analysis method for idiopathic epiretinal membrane Allegrini, Davide Montesano, Giovanni Marconi, Stefania Rosso, Nicoletta Ometto, Giovanni Raimondi, Raffaele Auricchio, Ferdinando Tsoutsanis, Panagiotis Semeraro, Francesco Cacciatori, Matteo Crabb, David P. Romano, Mario R. PLoS One Research Article PURPOSE: To introduce a novel method to quantitively analyse in three dimensions traction forces in a vast area of the ocular posterior pole. METHODS: Retrospective analysis of 14 eyes who underwent peeling surgery for idiopathic, symptomatic and progressive epiretinal membrane. The technique measures the shift in position of vascular crossings after surgery from a fixed point, which is the retinal pigmented epithelium. This shift is defined as the relaxation index (RI) and represents a measure of the postoperative movement of the retina due to released traction after surgery. RESULTS: Best-corrected visual acuity was significantly better than baseline at all follow ups while the RI had its maximum value at baseline. Moreover, we found a significant correlation between best-corrected visual acuity at 6 months and RI at baseline. CONCLUSION: While all previous published methods focused on bi-dimensional changes observed in a small region, this study introduces a three-dimensional assessment of tractional forces. Future integration of RI into built-in processing software will allow systematic three-dimensional measurement of intraretinal traction. Public Library of Science 2021-03-17 /pmc/articles/PMC7968655/ /pubmed/33730020 http://dx.doi.org/10.1371/journal.pone.0247192 Text en © 2021 Allegrini et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Allegrini, Davide Montesano, Giovanni Marconi, Stefania Rosso, Nicoletta Ometto, Giovanni Raimondi, Raffaele Auricchio, Ferdinando Tsoutsanis, Panagiotis Semeraro, Francesco Cacciatori, Matteo Crabb, David P. Romano, Mario R. A novel quantitative analysis method for idiopathic epiretinal membrane |
title | A novel quantitative analysis method for idiopathic epiretinal membrane |
title_full | A novel quantitative analysis method for idiopathic epiretinal membrane |
title_fullStr | A novel quantitative analysis method for idiopathic epiretinal membrane |
title_full_unstemmed | A novel quantitative analysis method for idiopathic epiretinal membrane |
title_short | A novel quantitative analysis method for idiopathic epiretinal membrane |
title_sort | novel quantitative analysis method for idiopathic epiretinal membrane |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968655/ https://www.ncbi.nlm.nih.gov/pubmed/33730020 http://dx.doi.org/10.1371/journal.pone.0247192 |
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