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A novel quantitative analysis method for idiopathic epiretinal membrane

PURPOSE: To introduce a novel method to quantitively analyse in three dimensions traction forces in a vast area of the ocular posterior pole. METHODS: Retrospective analysis of 14 eyes who underwent peeling surgery for idiopathic, symptomatic and progressive epiretinal membrane. The technique measur...

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Autores principales: Allegrini, Davide, Montesano, Giovanni, Marconi, Stefania, Rosso, Nicoletta, Ometto, Giovanni, Raimondi, Raffaele, Auricchio, Ferdinando, Tsoutsanis, Panagiotis, Semeraro, Francesco, Cacciatori, Matteo, Crabb, David P., Romano, Mario R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968655/
https://www.ncbi.nlm.nih.gov/pubmed/33730020
http://dx.doi.org/10.1371/journal.pone.0247192
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author Allegrini, Davide
Montesano, Giovanni
Marconi, Stefania
Rosso, Nicoletta
Ometto, Giovanni
Raimondi, Raffaele
Auricchio, Ferdinando
Tsoutsanis, Panagiotis
Semeraro, Francesco
Cacciatori, Matteo
Crabb, David P.
Romano, Mario R.
author_facet Allegrini, Davide
Montesano, Giovanni
Marconi, Stefania
Rosso, Nicoletta
Ometto, Giovanni
Raimondi, Raffaele
Auricchio, Ferdinando
Tsoutsanis, Panagiotis
Semeraro, Francesco
Cacciatori, Matteo
Crabb, David P.
Romano, Mario R.
author_sort Allegrini, Davide
collection PubMed
description PURPOSE: To introduce a novel method to quantitively analyse in three dimensions traction forces in a vast area of the ocular posterior pole. METHODS: Retrospective analysis of 14 eyes who underwent peeling surgery for idiopathic, symptomatic and progressive epiretinal membrane. The technique measures the shift in position of vascular crossings after surgery from a fixed point, which is the retinal pigmented epithelium. This shift is defined as the relaxation index (RI) and represents a measure of the postoperative movement of the retina due to released traction after surgery. RESULTS: Best-corrected visual acuity was significantly better than baseline at all follow ups while the RI had its maximum value at baseline. Moreover, we found a significant correlation between best-corrected visual acuity at 6 months and RI at baseline. CONCLUSION: While all previous published methods focused on bi-dimensional changes observed in a small region, this study introduces a three-dimensional assessment of tractional forces. Future integration of RI into built-in processing software will allow systematic three-dimensional measurement of intraretinal traction.
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spelling pubmed-79686552021-03-31 A novel quantitative analysis method for idiopathic epiretinal membrane Allegrini, Davide Montesano, Giovanni Marconi, Stefania Rosso, Nicoletta Ometto, Giovanni Raimondi, Raffaele Auricchio, Ferdinando Tsoutsanis, Panagiotis Semeraro, Francesco Cacciatori, Matteo Crabb, David P. Romano, Mario R. PLoS One Research Article PURPOSE: To introduce a novel method to quantitively analyse in three dimensions traction forces in a vast area of the ocular posterior pole. METHODS: Retrospective analysis of 14 eyes who underwent peeling surgery for idiopathic, symptomatic and progressive epiretinal membrane. The technique measures the shift in position of vascular crossings after surgery from a fixed point, which is the retinal pigmented epithelium. This shift is defined as the relaxation index (RI) and represents a measure of the postoperative movement of the retina due to released traction after surgery. RESULTS: Best-corrected visual acuity was significantly better than baseline at all follow ups while the RI had its maximum value at baseline. Moreover, we found a significant correlation between best-corrected visual acuity at 6 months and RI at baseline. CONCLUSION: While all previous published methods focused on bi-dimensional changes observed in a small region, this study introduces a three-dimensional assessment of tractional forces. Future integration of RI into built-in processing software will allow systematic three-dimensional measurement of intraretinal traction. Public Library of Science 2021-03-17 /pmc/articles/PMC7968655/ /pubmed/33730020 http://dx.doi.org/10.1371/journal.pone.0247192 Text en © 2021 Allegrini et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Allegrini, Davide
Montesano, Giovanni
Marconi, Stefania
Rosso, Nicoletta
Ometto, Giovanni
Raimondi, Raffaele
Auricchio, Ferdinando
Tsoutsanis, Panagiotis
Semeraro, Francesco
Cacciatori, Matteo
Crabb, David P.
Romano, Mario R.
A novel quantitative analysis method for idiopathic epiretinal membrane
title A novel quantitative analysis method for idiopathic epiretinal membrane
title_full A novel quantitative analysis method for idiopathic epiretinal membrane
title_fullStr A novel quantitative analysis method for idiopathic epiretinal membrane
title_full_unstemmed A novel quantitative analysis method for idiopathic epiretinal membrane
title_short A novel quantitative analysis method for idiopathic epiretinal membrane
title_sort novel quantitative analysis method for idiopathic epiretinal membrane
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968655/
https://www.ncbi.nlm.nih.gov/pubmed/33730020
http://dx.doi.org/10.1371/journal.pone.0247192
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