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Co‐occurrence of germline pathogenic variants for different hereditary cancer syndromes in patients with Lynch syndrome
BACKGROUND: Lynch syndrome (LS) is a hereditary condition characterized by a high risk of colorectal cancer, endometrial cancer, and other neoplasia associated with germline alterations in DNA mismatch repair genes. The classical genetic diagnostic strategy for LS consists of the Sanger sequencing o...
Autores principales: | Ferrer‐Avargues, Rosario, Castillejo, María Isabel, Dámaso, Estela, Díez‐Obrero, Virginia, Garrigos, Noemí, Molina, Tatiana, Codoñer‐Alejos, Alan, Segura, Ángel, Sánchez‐Heras, Ana Beatriz, Castillejo, Adela, Soto, José Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968885/ https://www.ncbi.nlm.nih.gov/pubmed/33630411 http://dx.doi.org/10.1002/cac2.12134 |
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