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Regulatory B cells: TIM‐1, transplant tolerance, and rejection

Regulatory B cells (Bregs) ameliorate autoimmune disease and prevent allograft rejection. Conversely, they hinder effective clearance of pathogens and malignancies. Breg activity is mainly attributed to IL‐10 expression, but also utilizes additional regulatory mechanisms such as TGF‐β, FasL, IL‐35,...

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Detalles Bibliográficos
Autores principales: Cherukuri, Aravind, Mohib, Kanishka, Rothstein, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7968891/
https://www.ncbi.nlm.nih.gov/pubmed/33484008
http://dx.doi.org/10.1111/imr.12933

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