RNA polymerase clamp conformational dynamics: long-lived states and modulation by crowding, cations, and nonspecific DNA binding

The RNA polymerase (RNAP) clamp, a mobile structural element conserved in RNAP from all domains of life, has been proposed to play critical roles at different stages of transcription. In previous work, we demonstrated using single-molecule Förster resonance energy transfer (smFRET) that RNAP clamp i...

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Detalles Bibliográficos
Autores principales: Mazumder, Abhishek, Wang, Anna, Uhm, Heesoo, Ebright, Richard H, Kapanidis, Achillefs N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969002/
https://www.ncbi.nlm.nih.gov/pubmed/33589919
http://dx.doi.org/10.1093/nar/gkab074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969002/
https://www.ncbi.nlm.nih.gov/pubmed/33589919
http://dx.doi.org/10.1093/nar/gkab074

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