Optogenetic control of Neisseria meningitidis Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein

Optogenetic control of CRISPR–Cas9 systems has significantly improved our ability to perform genome perturbations in living cells with high precision in time and space. As new Cas orthologues with advantageous properties are rapidly being discovered and engineered, the need for straightforward strat...

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Detalles Bibliográficos
Autores principales: Hoffmann, Mareike D, Mathony, Jan, Upmeier zu Belzen, Julius, Harteveld, Zander, Aschenbrenner, Sabine, Stengl, Christina, Grimm, Dirk, Correia, Bruno E, Eils, Roland, Niopek, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969004/
https://www.ncbi.nlm.nih.gov/pubmed/33330940
http://dx.doi.org/10.1093/nar/gkaa1198

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