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Restriction of an intron size en route to endothermy

Ca(2+)-insensitive and -sensitive E1 subunits of the 2-oxoglutarate dehydrogenase complex (OGDHC) regulate tissue-specific NADH and ATP supply by mutually exclusive OGDH exons 4a and 4b. Here we show that their splicing is enforced by distant lariat branch points (dBPs) located near the 5′ splice si...

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Detalles Bibliográficos
Autores principales:	Královičová, Jana, Borovská, Ivana, Pengelly, Reuben, Lee, Eunice, Abaffy, Pavel, Šindelka, Radek, Grutzner, Frank, Vořechovský, Igor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969005/ https://www.ncbi.nlm.nih.gov/pubmed/33550394 http://dx.doi.org/10.1093/nar/gkab046

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