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Interplay of folded domains and the disordered low-complexity domain in mediating hnRNPA1 phase separation
Liquid–liquid phase separation underlies the membrane-less compartmentalization of cells. Intrinsically disordered low-complexity domains (LCDs) often mediate phase separation, but how their phase behavior is modulated by folded domains is incompletely understood. Here, we interrogate the interplay...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969017/ https://www.ncbi.nlm.nih.gov/pubmed/33577679 http://dx.doi.org/10.1093/nar/gkab063 |