Mechanisms of spacer acquisition by sequential assembly of the adaptation module in Synechocystis

CRISPR–Cas immune systems process and integrate short fragments of DNA from new invaders as spacers into the host CRISPR locus to establish molecular memory of prior infection, which is also known as adaptation in the field. Some CRISPR–Cas systems rely on Cas1 and Cas2 to complete the adaptation pr...

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Detalles Bibliográficos
Autores principales: Wu, Chengyong, Tang, Dongmei, Cheng, Jie, Hu, Daojun, Yang, Zejing, Ma, Xue, He, Haihuai, Yao, Shaohua, Fu, Tian-Min, Yu, Yamei, Chen, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969031/
https://www.ncbi.nlm.nih.gov/pubmed/33619565
http://dx.doi.org/10.1093/nar/gkab105

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