Mutations in genes affecting DNA methylation enhances responses to decitabine in patients with myelodysplastic syndrome

BACKGROUND/AIMS: In this study, we tested whether mutations in the methylation pathway genes ten-eleven-translocation 2 (TET2) and DNA methyltransferase gene 3A (DNMT3A) improve the responses of patients with myelodysplastic syndrome (MDS) to decitabine. METHODS: We retrospectively sequenced the TET...

Descripción completa

Detalles Bibliográficos
Autores principales: Jung, Hyun Ae, Jung, Chul Won, Jang, Jun Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969079/
https://www.ncbi.nlm.nih.gov/pubmed/33086776
http://dx.doi.org/10.3904/kjim.2019.385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969079/
https://www.ncbi.nlm.nih.gov/pubmed/33086776
http://dx.doi.org/10.3904/kjim.2019.385

Ejemplares similares