Cargando…
Toward improved adherence: a text message intervention in an human immunodeficiency virus pediatric clinic in Guatemala City
As access to human immunodeficiency virus treatment expands in Low to Middle Income Countries, it becomes critical to develop and test strategies to improve adherence and ensure efficacy. Text messaging improves adherence to antiretroviral treatment antiretroviral treatment in some patient populatio...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969223/ https://www.ncbi.nlm.nih.gov/pubmed/33725842 http://dx.doi.org/10.1097/MD.0000000000024867 |
_version_ | 1783666198504800256 |
---|---|
author | Sánchez, Sergio Alejandro Ramay, Brooke M. Zook, Jessica de Leon, Oscar Peralta, Ricardo Juarez, Julio Cocohoba, Jennifer |
author_facet | Sánchez, Sergio Alejandro Ramay, Brooke M. Zook, Jessica de Leon, Oscar Peralta, Ricardo Juarez, Julio Cocohoba, Jennifer |
author_sort | Sánchez, Sergio Alejandro |
collection | PubMed |
description | As access to human immunodeficiency virus treatment expands in Low to Middle Income Countries, it becomes critical to develop and test strategies to improve adherence and ensure efficacy. Text messaging improves adherence to antiretroviral treatment antiretroviral treatment in some patient populations, but data surrounding the use of these tools is sparse in pediatric and adolescent patients in low to middle income countries. We evaluated if a text message intervention can improve antiretroviral treatment adherence while accounting for cell phone access, patterns of use, and willingness to receive text messages. We carried out a cross sectional study to understand willingness of receiving text message reminders, followed by a randomized controlled trial to assess effectiveness of text message intervention. Enrolled participants were randomized to receive standard care with regular clinic visits, or standard care plus short message service reminders. Adherence was measured 3 times during the study period using a 4-day Recall Questionnaire. Outcome was measured based on differences in the average adherence between the intervention and control group at each time point (baseline, 3 months, 6 months). Most respondents were willing to receive text message adherence reminders (81.1%, n = 53). Respondent literacy, travel time to clinic, cell phone access, and patterns of use were significantly associated with willingness. In the randomized trial the intervention group (n = 50) experienced a small but significant mean improvement in adherence over the six-month period (4%, P < .01) whereas the control group (n = 50) did not (mean improvement: 0.8%, P = .64). Text message interventions effectively support antiretroviral adherence in pediatric patients living with human immunodeficiency virus. Studies designed to assess the impact of text messaging interventions must examine local context for cellular phone infrastructure and use and must account for potential loss to follow up when patients miss appointments and study assessments. |
format | Online Article Text |
id | pubmed-7969223 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-79692232021-03-18 Toward improved adherence: a text message intervention in an human immunodeficiency virus pediatric clinic in Guatemala City Sánchez, Sergio Alejandro Ramay, Brooke M. Zook, Jessica de Leon, Oscar Peralta, Ricardo Juarez, Julio Cocohoba, Jennifer Medicine (Baltimore) 4850 As access to human immunodeficiency virus treatment expands in Low to Middle Income Countries, it becomes critical to develop and test strategies to improve adherence and ensure efficacy. Text messaging improves adherence to antiretroviral treatment antiretroviral treatment in some patient populations, but data surrounding the use of these tools is sparse in pediatric and adolescent patients in low to middle income countries. We evaluated if a text message intervention can improve antiretroviral treatment adherence while accounting for cell phone access, patterns of use, and willingness to receive text messages. We carried out a cross sectional study to understand willingness of receiving text message reminders, followed by a randomized controlled trial to assess effectiveness of text message intervention. Enrolled participants were randomized to receive standard care with regular clinic visits, or standard care plus short message service reminders. Adherence was measured 3 times during the study period using a 4-day Recall Questionnaire. Outcome was measured based on differences in the average adherence between the intervention and control group at each time point (baseline, 3 months, 6 months). Most respondents were willing to receive text message adherence reminders (81.1%, n = 53). Respondent literacy, travel time to clinic, cell phone access, and patterns of use were significantly associated with willingness. In the randomized trial the intervention group (n = 50) experienced a small but significant mean improvement in adherence over the six-month period (4%, P < .01) whereas the control group (n = 50) did not (mean improvement: 0.8%, P = .64). Text message interventions effectively support antiretroviral adherence in pediatric patients living with human immunodeficiency virus. Studies designed to assess the impact of text messaging interventions must examine local context for cellular phone infrastructure and use and must account for potential loss to follow up when patients miss appointments and study assessments. Lippincott Williams & Wilkins 2021-03-12 /pmc/articles/PMC7969223/ /pubmed/33725842 http://dx.doi.org/10.1097/MD.0000000000024867 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 |
spellingShingle | 4850 Sánchez, Sergio Alejandro Ramay, Brooke M. Zook, Jessica de Leon, Oscar Peralta, Ricardo Juarez, Julio Cocohoba, Jennifer Toward improved adherence: a text message intervention in an human immunodeficiency virus pediatric clinic in Guatemala City |
title | Toward improved adherence: a text message intervention in an human immunodeficiency virus pediatric clinic in Guatemala City |
title_full | Toward improved adherence: a text message intervention in an human immunodeficiency virus pediatric clinic in Guatemala City |
title_fullStr | Toward improved adherence: a text message intervention in an human immunodeficiency virus pediatric clinic in Guatemala City |
title_full_unstemmed | Toward improved adherence: a text message intervention in an human immunodeficiency virus pediatric clinic in Guatemala City |
title_short | Toward improved adherence: a text message intervention in an human immunodeficiency virus pediatric clinic in Guatemala City |
title_sort | toward improved adherence: a text message intervention in an human immunodeficiency virus pediatric clinic in guatemala city |
topic | 4850 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969223/ https://www.ncbi.nlm.nih.gov/pubmed/33725842 http://dx.doi.org/10.1097/MD.0000000000024867 |
work_keys_str_mv | AT sanchezsergioalejandro towardimprovedadherenceatextmessageinterventioninanhumanimmunodeficiencyviruspediatricclinicinguatemalacity AT ramaybrookem towardimprovedadherenceatextmessageinterventioninanhumanimmunodeficiencyviruspediatricclinicinguatemalacity AT zookjessica towardimprovedadherenceatextmessageinterventioninanhumanimmunodeficiencyviruspediatricclinicinguatemalacity AT deleonoscar towardimprovedadherenceatextmessageinterventioninanhumanimmunodeficiencyviruspediatricclinicinguatemalacity AT peraltaricardo towardimprovedadherenceatextmessageinterventioninanhumanimmunodeficiencyviruspediatricclinicinguatemalacity AT juarezjulio towardimprovedadherenceatextmessageinterventioninanhumanimmunodeficiencyviruspediatricclinicinguatemalacity AT cocohobajennifer towardimprovedadherenceatextmessageinterventioninanhumanimmunodeficiencyviruspediatricclinicinguatemalacity |