Cargando…

A single-arm, open-label, intervention study to investigate the improvement of glucose tolerance after administration of the 5-aminolevulinic acid (5-ALA) in the patients with mitochondrial diabetes mellitus

BACKGROUND: Mitochondrial diabetes mellitus (MDM) is characterized by maternal inheritance, progressive neurosensory deafness, insulin secretory disorder, and progressive microvascular complications. Mitochondria are critical organelles that provide energy in the form of adenosine triphosphate (ATP)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nakamura, Yuta, Haraguchi, Ai, Shigeno, Riyoko, Ito, Ayako, Horie, Ichiro, Kawakami, Atsushi, Abiru, Norio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	4300
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969291/ https://www.ncbi.nlm.nih.gov/pubmed/33725905 http://dx.doi.org/10.1097/MD.0000000000025100

Ejemplares similares

ODP158 A Pilot Trial on the Efficacy of 5-Aminolevulinic Acid on Glucose Tolerance in Patients with Maternally Inherited Diabetes and Deafness
por: Nakamura, Yuta, et al.
Publicado: (2022)

Pilot Trial on the Effect of 5-Aminolevulinic Acid on Glucose Tolerance in Patients with Maternally Inherited Diabetes and Deafness
por: Nakamura, Yuta, et al.
Publicado: (2022)

Impact of glucagon response on early postprandial glucose excursions irrespective of residual β‐cell function in type 1 diabetes: A cross‐sectional study using a mixed meal tolerance test
por: Ito, Ayako, et al.
Publicado: (2021)

The effect of luseogliflozin on bone microarchitecture in older patients with type 2 diabetes: study protocol for a randomized controlled pilot trial using second-generation, high-resolution, peripheral quantitative computed tomography (HR-pQCT)
por: Haraguchi, Ai, et al.
Publicado: (2020)

Photodynamic Detection of Peritoneal Metastases Using 5-Aminolevulinic Acid (ALA)
por: Yonemura, Yutaka, et al.
Publicado: (2017)

The effects of the heme precursor 5-aminolevulinic acid (ALA) on REV-ERBα activation
por: Yamashita, Kohei, et al.
Publicado: (2014)

In vitro evaluation of 5-aminolevulinic acid (ALA) loaded PLGA nanoparticles
por: Shi, Lei, et al.
Publicado: (2013)

Alleviation of Lead Stress on Sage Plant by 5-Aminolevulinic Acid (ALA)
por: El-Shora, Hamed M., et al.
Publicado: (2021)

Safety and Mode of Action of Diabetes Medications in comparison with 5-Aminolevulinic Acid (5-ALA)
por: Rehani, Peter R., et al.
Publicado: (2019)

The Association Between Body Mass Index and All-Cause Mortality in Patients With Type 2 Diabetes Mellitus: A 5.5-Year Prospective Analysis
por: Kuo, Jeng-Fu, et al.
Publicado: (2015)

Impaired early‐phase suppression of glucagon secretion after glucose load is associated with insulin requirement during pregnancy in gestational diabetes
por: Horie, Ichiro, et al.
Publicado: (2019)

HGG-19. 5-AMINOLEVULINIC ACID (5-ALA)-GUIDED RESECTION OF PEDIATRIC BRAIN TUMORS
por: Schwake, Michael, et al.
Publicado: (2021)

SURG-08. 5-Aminolevulinic acid (5-ALA)-guided resection of pediatric brain tumors
por: Schwake, Michael, et al.
Publicado: (2022)

Thyroid-associated orbitopathy in patients with thyroid carcinoma: A case report of 5 cases
por: Yu, Peng, et al.
Publicado: (2017)

Association of microRNA-related gene XPO5 rs11077 polymorphism with susceptibility to thyroid cancer
por: Wen, Jing, et al.
Publicado: (2017)

The correlation between serum free thyroxine and regression of dyslipidemia in adult males: A 4.5-year prospective study
por: Wang, Haoyu, et al.
Publicado: (2017)

Maturity-Onset diabetes of the young type 5 treated with the glucagon-like peptide-1 receptor agonist: A case report
por: Terakawa, Aiko, et al.
Publicado: (2020)

Association between uric acid level and incidence of albuminuria in patients with type 2 diabetes mellitus: A 4.5-year cohort study
por: Lai, Yun-Ju, et al.
Publicado: (2021)

Sex differences in insulin and glucagon responses for glucose homeostasis in young healthy Japanese adults
por: Horie, Ichiro, et al.
Publicado: (2018)

Effects of saxagliptin add-on therapy to insulin on blood glycemic fluctuations in patients with type 2 diabetes: A randomized, control, open-labeled trial
por: Li, Feng-fei, et al.
Publicado: (2016)

Predicting non-small-volume central lymph node metastases (>5 or ≥2 mm) preoperatively in cN0 papillary thyroid microcarcinoma without extrathyroidal extension
por: Shou, Jin-Duo, et al.
Publicado: (2020)

Prediction mode of more than 5 central lymph nodes metastases in clinically node-negative ipsilateral papillary thyroid carcinoma with tumor size 1 to 4 cm
por: Jin, Lei, et al.
Publicado: (2020)

Alleviation of Shade Stress in Chinese Yew (Taxus chinensis) Seedlings with 5-Aminolevulinic Acid (ALA)
por: Wu, Liuliu, et al.
Publicado: (2023)

Clinical evaluations of pituitary apoplexy in incidental nonfunctional pituitary adenomas
por: Takeshita, Kaori, et al.
Publicado: (2022)

Palisaded neutrophilic and granulomatous dermatitis as a novel cause of hypercalcemia: A case report
por: Kono, Michihito, et al.
Publicado: (2017)

THE USE OF 5-AMINOLEVULINIC ACID (5-ALA) IN HIGH-GRADE GLIOMA SURGERY, A SINGLE CANADIAN CENTER EXPERIENCE
por: LeBlanc, Félix, et al.
Publicado: (2023)

5-Aminolevulinic Acid (ALA) Alleviated Salinity Stress in Cucumber Seedlings by Enhancing Chlorophyll Synthesis Pathway
por: Wu, Yue, et al.
Publicado: (2018)

Effects of tofogliflozin on adrenocorticotropic hormone, renin and aldosterone, and cortisol levels in elderly patients with diabetes mellitus: A retrospective study of a patient cohort
por: Higashikawa, Toshihiro, et al.
Publicado: (2021)

Clinical investigation of a unique type of hypothalamic adrenal insufficiency
por: Takeshita, Kaori, et al.
Publicado: (2022)

Investigation of the metabolic and endocrinological differences between daily and weekly growth hormone replacement therapy, somapacitan, in patients with adult growth hormone deficiency: A real-world pilot study
por: Abe, Ichiro, et al.
Publicado: (2023)

5-Aminolevulinic Acid (5-ALA)-Induced Protoporphyrin IX Fluorescence by Glioma Cells—A Fluorescence Microscopy Clinical Study
por: Pacioni, Simone, et al.
Publicado: (2022)

Effect of denosumab, a human monoclonal antibody of receptor activator of nuclear factor kappa-B ligand (RANKL), upon glycemic and metabolic parameters: Effect of denosumab on glycemic parameters
por: Abe, Ichiro, et al.
Publicado: (2019)

Hospitalization with hypoglycemia in patients without diabetes mellitus: A retrospective study using a national inpatient database in Japan, 2008–2012
por: Sako, Akahito, et al.
Publicado: (2017)

Syndrome of inappropriate secretion of thyroid-stimulating hormone in a subject with galactorrhea and menstrual disorder and undergoing infertility treatment: Case report
por: Kaneto, Hideaki, et al.
Publicado: (2021)

Amelioration of hypercalcemia by cinacalcet treatment in a subject with relapsing acquired hypocalciuric hypercalcemia: A case report
por: Sanada, Junpei, et al.
Publicado: (2021)

Aminolevulinic Acid (ALA) as a Prodrug in Photodynamic Therapy of Cancer
por: Wachowska, Małgorzata, et al.
Publicado: (2011)

Case report of severe hypoglycemic alcoholic ketoacidosis: A possible pitfall in diagnosis of ketoacidosis
por: Okauchi, Seizo, et al.
Publicado: (2022)

Efficacy of 5-Aminolevulinic Acid (ALA)-Photodynamic Therapy (PDT) in Refractory Vulvar Lichen Sclerosus: Preliminary Results
por: Zhang, Fenghua, et al.
Publicado: (2021)

The 5-Aminolevulinic Acid (5-ALA) Supplement Enhances PSII Photochemical Activity and Antioxidant Activity in the Late Growth Promotion of Pseudostellaria heterophylla
por: Ma, Julin, et al.
Publicado: (2022)

A case series pilot study on the combination of 5-aminolevulinic acid and photodynamic therapy (ALA-PDT) for treatment of vitiligo
por: Zhang, YunJie, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_du5o2hnhbmadrf2edrspl8s9f6