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Chinese herbal compounds containing scorpion in the treatment of epilepsy: A protocol for systematic review and meta-analysis
BACKGROUND: Epilepsy is 1 of the common neurodevelopmental diseases. It can affect about 0.5% to 1.0% of the population regardless of their race and social class. Despite the development of a wide range of treatments, there remaining about one-third of patients still experience seizures. Chinese her...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969296/ https://www.ncbi.nlm.nih.gov/pubmed/33725915 http://dx.doi.org/10.1097/MD.0000000000025134 |
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author | Rong, Ping Fu, Qianfang Zhang, Xilian Liu, Xuan Yang, Jie Wang, Xin Wang, Shuai Liu, Hui Ma, Rong Nie, Lianghui Ma, Rong |
author_facet | Rong, Ping Fu, Qianfang Zhang, Xilian Liu, Xuan Yang, Jie Wang, Xin Wang, Shuai Liu, Hui Ma, Rong Nie, Lianghui Ma, Rong |
author_sort | Rong, Ping |
collection | PubMed |
description | BACKGROUND: Epilepsy is 1 of the common neurodevelopmental diseases. It can affect about 0.5% to 1.0% of the population regardless of their race and social class. Despite the development of a wide range of treatments, there remaining about one-third of patients still experience seizures. Chinese herbal compounds containing scorpion (CHCCS) have shown an outstanding curative effect on nerve protection and epilepsy. But there's no study to assess its clinical efficacy and safety. METHODS: Each data of CHCCS in treating epilepsy from related English and Chinese databases will be searched. The primary outcome is the efficacy of the CHCCS on epilepsy. And the secondary outcomes include recurrence rate and side effects. The risk of bias will be assessed, and RevMan5.3 and Stata14.0 will be performed for meta-analysis. Finally, we will assess the level of the resulting evidence. RESULTS: The results of the study will be combined with current evidence and published in a peer-reviewed journal. CONCLUSIONS: This study will specifically investigate the effectiveness and safety of CHCCS in treating epilepsy. INPLASY REGISTRATION NUMBER: INPLASY202120056. |
format | Online Article Text |
id | pubmed-7969296 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-79692962021-03-18 Chinese herbal compounds containing scorpion in the treatment of epilepsy: A protocol for systematic review and meta-analysis Rong, Ping Fu, Qianfang Zhang, Xilian Liu, Xuan Yang, Jie Wang, Xin Wang, Shuai Liu, Hui Ma, Rong Nie, Lianghui Ma, Rong Medicine (Baltimore) 3800 BACKGROUND: Epilepsy is 1 of the common neurodevelopmental diseases. It can affect about 0.5% to 1.0% of the population regardless of their race and social class. Despite the development of a wide range of treatments, there remaining about one-third of patients still experience seizures. Chinese herbal compounds containing scorpion (CHCCS) have shown an outstanding curative effect on nerve protection and epilepsy. But there's no study to assess its clinical efficacy and safety. METHODS: Each data of CHCCS in treating epilepsy from related English and Chinese databases will be searched. The primary outcome is the efficacy of the CHCCS on epilepsy. And the secondary outcomes include recurrence rate and side effects. The risk of bias will be assessed, and RevMan5.3 and Stata14.0 will be performed for meta-analysis. Finally, we will assess the level of the resulting evidence. RESULTS: The results of the study will be combined with current evidence and published in a peer-reviewed journal. CONCLUSIONS: This study will specifically investigate the effectiveness and safety of CHCCS in treating epilepsy. INPLASY REGISTRATION NUMBER: INPLASY202120056. Lippincott Williams & Wilkins 2021-03-12 /pmc/articles/PMC7969296/ /pubmed/33725915 http://dx.doi.org/10.1097/MD.0000000000025134 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | 3800 Rong, Ping Fu, Qianfang Zhang, Xilian Liu, Xuan Yang, Jie Wang, Xin Wang, Shuai Liu, Hui Ma, Rong Nie, Lianghui Ma, Rong Chinese herbal compounds containing scorpion in the treatment of epilepsy: A protocol for systematic review and meta-analysis |
title | Chinese herbal compounds containing scorpion in the treatment of epilepsy: A protocol for systematic review and meta-analysis |
title_full | Chinese herbal compounds containing scorpion in the treatment of epilepsy: A protocol for systematic review and meta-analysis |
title_fullStr | Chinese herbal compounds containing scorpion in the treatment of epilepsy: A protocol for systematic review and meta-analysis |
title_full_unstemmed | Chinese herbal compounds containing scorpion in the treatment of epilepsy: A protocol for systematic review and meta-analysis |
title_short | Chinese herbal compounds containing scorpion in the treatment of epilepsy: A protocol for systematic review and meta-analysis |
title_sort | chinese herbal compounds containing scorpion in the treatment of epilepsy: a protocol for systematic review and meta-analysis |
topic | 3800 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969296/ https://www.ncbi.nlm.nih.gov/pubmed/33725915 http://dx.doi.org/10.1097/MD.0000000000025134 |
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