IgA transcytosis and antigen recognition govern ovarian cancer immunity

Most ovarian cancers are infiltrated by prognostically relevant activated T cells(1–3), yet exhibit low response rates to immune checkpoint inhibitors(4). Memory B cell and plasma cell infiltrates have previously been associated with better outcomes in ovarian cancer(5,6), but the nature and functio...

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Detalles Bibliográficos
Autores principales: Biswas, Subir, Mandal, Gunjan, Payne, Kyle K., Anadon, Carmen M., Gatenbee, Chandler D., Chaurio, Ricardo A., Costich, Tara Lee, Moran, Carlos, Harro, Carly M., Rigolizzo, Kristen E., Mine, Jessica A., Trillo-Tinoco, Jimena, Sasamoto, Naoko, Terry, Kathryn L., Marchion, Douglas, Buras, Andrea, Wenham, Robert M., Yu, Xiaoqing, Townsend, Mary K., Tworoger, Shelley S., Rodriguez, Paulo C., Anderson, Alexander R., Conejo-Garcia, Jose R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969354/
https://www.ncbi.nlm.nih.gov/pubmed/33536615
http://dx.doi.org/10.1038/s41586-020-03144-0

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