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EZH2 is required for parathyroid and thymic development through differentiation of the third pharyngeal pouch endoderm

The Ezh2 gene encodes a histone methyltransferase of the polycomb repressive complex 2 that methylates histone H3 lysine 27. In this study, we investigated whether EZH2 has a role in the development of the pharyngeal apparatus and whether it regulates the expression of the Tbx1 gene, which encodes a...

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Detalles Bibliográficos
Autores principales: Caprio, Cinzia, Lania, Gabriella, Bilio, Marchesa, Ferrentino, Rosa, Chen, Li, Baldini, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969367/
https://www.ncbi.nlm.nih.gov/pubmed/33608392
http://dx.doi.org/10.1242/dmm.046789