Nitric Oxide/Cyclic GMP-Dependent Calcium Signalling Mediates IL-6- and TNF-α-Induced Expression of Glial Fibrillary Acid Protein

Astrocyte activation is characterized by hypertrophy with increased glial fibrillary acidic protein (GFAP), whose expression may involve pro-inflammatory cytokines. In this study, the effects of pro-inflammatory IL-6 and TNF-α and anti-inflammatory cytokines IL-4 and IL-10 on nitric oxide (NO)/cycli...

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Detalles Bibliográficos
Autores principales: Sticozzi, Claudia, Belmonte, Giuseppe, Frosini, Maria, Pessina, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969574/
https://www.ncbi.nlm.nih.gov/pubmed/32964397
http://dx.doi.org/10.1007/s12031-020-01708-3

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