p97/VCP is highly expressed in the stem-like cells of breast cancer and controls cancer stemness partly through the unfolded protein response

p97/VCP, an evolutionarily concerned ATPase, partakes in multiple cellular proteostatic processes, including the endoplasmic reticulum (ER)-associated protein degradation (ERAD). Elevated expression of p97 is common in many cancers and is often associated with poor survival. Here we report that the...

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Detalles Bibliográficos
Autores principales: Li, Chuang, Huang, Yongsheng, Fan, Qianqian, Quan, Hongyang, Dong, Yeqing, Nie, Meng, Wang, Jiaqi, Xie, Fucun, Ji, Jiang, Zhou, Lan, Zheng, Zhi, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969628/
https://www.ncbi.nlm.nih.gov/pubmed/33731668
http://dx.doi.org/10.1038/s41419-021-03555-5

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