Treatment with the calcineurin inhibitor and immunosuppressant cyclosporine A impairs sensorimotor gating in Dark Agouti rats

RATIONALE: Calcineurin is a protein regulating cytokine expression in T lymphocytes and calcineurin inhibitors such as cyclosporine A (CsA) are widely used for immunosuppressive therapy. It also plays a functional role in distinct neuronal processes in the central nervous system. Disturbed informati...

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Detalles Bibliográficos
Autores principales: Brosda, Jan, Becker, Thorsten, Richter, Mathis, Jakobs, Marie, Hörbelt, Tina, Bendix, Ivo, Lückemann, Laura, Schedlowski, Manfred, Hadamitzky, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969700/
https://www.ncbi.nlm.nih.gov/pubmed/33349900
http://dx.doi.org/10.1007/s00213-020-05751-1

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