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Cleavage and Polyadenylation Specific Factor 1 Promotes Tumor Progression via Alternative Polyadenylation and Splicing in Hepatocellular Carcinoma

Alternative polyadenylation (APA) is an important post-transcriptional regulatory mechanism required for cleavage and polyadenylation (CPA) of the 3′ untranslated region (3′ UTR) of mRNAs. Several aberrant APA events have been reported in hepatocellular carcinoma (HCC). However, the regulatory mecha...

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Detalles Bibliográficos
Autores principales: Chen, Shi-lu, Zhu, Zhong-xu, Yang, Xia, Liu, Li-li, He, Yang-fan, Yang, Ming-ming, Guan, Xin-yuan, Wang, Xin, Yun, Jing-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969726/
https://www.ncbi.nlm.nih.gov/pubmed/33748106
http://dx.doi.org/10.3389/fcell.2021.616835