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Renal Dnase1 expression is regulated by FGF23 but loss of Dnase1 does not alter renal phosphate handling
Fibroblast growth factor 23 (FGF23) is a bone-derived endocrine hormone that regulates phosphate and vitamin D metabolism. In models of FGF23 excess, renal deoxyribonuclease 1 (Dnase1) mRNA expression is downregulated. Dnase-1 is an endonuclease which binds monomeric actin. We investigated whether F...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969776/ https://www.ncbi.nlm.nih.gov/pubmed/33731726 http://dx.doi.org/10.1038/s41598-021-84735-3 |