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Somatic and de novo Germline Variants of MEDs in Human Neural Tube Defects

BACKGROUND: Neural tube defects (NTDs) are among the most common and severe congenital defects in humans. Their genetic etiology is complex and remains poorly understood. The Mediator complex (MED) plays a vital role in neural tube development in animal models. However, no studies have yet examined...

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Detalles Bibliográficos
Autores principales:	Tian, Tian, Cao, Xuanye, Chen, Yongyan, Jin, Lei, Li, Zhiwen, Han, Xiao, Lin, Ying, Wlodarczyk, Bogdan J., Finnell, Richard H., Yuan, Zhengwei, Wang, Linlin, Ren, Aiguo, Lei, Yunping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969791/ https://www.ncbi.nlm.nih.gov/pubmed/33748132 http://dx.doi.org/10.3389/fcell.2021.641831

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