Abnormal Rat Cortical Development Induced by Ventricular Injection of rHMGB1 Mimics the Pathophysiology of Human Cortical Dysplasia

Cortical dysplasia (CD) is a common cause of drug-resistant epilepsy. Increasing studies have implicated innate immunity in CD with epilepsy. However, it is unclear whether innate immune factors induce epileptogenic CD. Here, we injected recombinant human high mobility group box 1 (rHMGB1) into embr...

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Detalles Bibliográficos
Autores principales: Yang, Xiaolin, Zhang, Xiaoqing, Ma, Yuanshi, Wang, Zhongke, Huang, Kaixuan, Liu, Guolong, Shen, Kaifeng, Zhu, Gang, Wang, Tingting, Lv, Shengqing, Zhang, Chunqing, Yang, Hui, Liu, Shiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969805/
https://www.ncbi.nlm.nih.gov/pubmed/33748118
http://dx.doi.org/10.3389/fcell.2021.634405

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