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DNA Methylation of TLR4, VEGFA, and DEFA5 Is Associated With Necrotizing Enterocolitis in Preterm Infants

Background: Epigenetic changes, such as DNA methylation, may contribute to an increased susceptibility for developing necrotizing enterocolitis (NEC) in preterm infants. We assessed DNA methylation in five NEC-associated genes, selected from literature: EPO, VEGFA, ENOS, DEFA5, and TLR4 in infants w...

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Detalles Bibliográficos
Autores principales: Klerk, Daphne H., Plösch, Torsten, Verkaik-Schakel, Rikst Nynke, Hulscher, Jan B. F., Kooi, Elisabeth M. W., Bos, Arend F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969816/
https://www.ncbi.nlm.nih.gov/pubmed/33748044
http://dx.doi.org/10.3389/fped.2021.630817