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Inhibition of HMGB1 Suppresses Hepatocellular Carcinoma Progression via HIPK2-Mediated Autophagic Degradation of ZEB1
Autophagy is a conserved catabolic process maintaining cellular homeostasis and reportedly plays a critical role in tumor progression. Accumulating data show that autophagic activity is inhibited in hepatocellular carcinoma. However, the underlying molecular basis of impaired autophagy in HCC remain...
Autores principales: | Zhu, Wei, Li, Jun, Zhang, Yuheng, Zhu, Zhengyi, Liu, Hanyi, Lin, Yunzhen, Hu, Anyin, Zhou, Jingchao, Ren, Haozhen, Shi, Xiaolei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969871/ https://www.ncbi.nlm.nih.gov/pubmed/33747917 http://dx.doi.org/10.3389/fonc.2021.599124 |
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