Current Management of Membranous Urethral Strictures Due to Radiation

Radiotherapy is a frequently used treatment for prostate cancer. It does not only causes the intended damage to cancer cells, but also affects healthy surrounding tissue. As a result radiation-induced urethral strictures occur in 2.2% of prostate cancer patients. Management of urethral strictures is...

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Detalles Bibliográficos
Autores principales: Waterloos, Marjan, Martins, Francisco, Verla, Wesley, Kluth, Luis Alex, Lumen, Nicolaas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Surgery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969877/
https://www.ncbi.nlm.nih.gov/pubmed/33748181
http://dx.doi.org/10.3389/fsurg.2021.635060
Descripción
Sumario:Radiotherapy is a frequently used treatment for prostate cancer. It does not only causes the intended damage to cancer cells, but also affects healthy surrounding tissue. As a result radiation-induced urethral strictures occur in 2.2% of prostate cancer patients. Management of urethral strictures is challenging due to the presence of poor vascularized tissue for reconstruction and the proximity of the sphincter, which can impair the functional outcome. This review provides a literature overview of risk factors, diagnostics and management of radiation-induced urethral strictures.

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