Current Management of Membranous Urethral Strictures Due to Radiation

Radiotherapy is a frequently used treatment for prostate cancer. It does not only causes the intended damage to cancer cells, but also affects healthy surrounding tissue. As a result radiation-induced urethral strictures occur in 2.2% of prostate cancer patients. Management of urethral strictures is...

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Detalles Bibliográficos
Autores principales: Waterloos, Marjan, Martins, Francisco, Verla, Wesley, Kluth, Luis Alex, Lumen, Nicolaas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Surgery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969877/
https://www.ncbi.nlm.nih.gov/pubmed/33748181
http://dx.doi.org/10.3389/fsurg.2021.635060
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author Waterloos, Marjan
Martins, Francisco
Verla, Wesley
Kluth, Luis Alex
Lumen, Nicolaas
author_facet Waterloos, Marjan
Martins, Francisco
Verla, Wesley
Kluth, Luis Alex
Lumen, Nicolaas
author_sort Waterloos, Marjan
collection PubMed
description Radiotherapy is a frequently used treatment for prostate cancer. It does not only causes the intended damage to cancer cells, but also affects healthy surrounding tissue. As a result radiation-induced urethral strictures occur in 2.2% of prostate cancer patients. Management of urethral strictures is challenging due to the presence of poor vascularized tissue for reconstruction and the proximity of the sphincter, which can impair the functional outcome. This review provides a literature overview of risk factors, diagnostics and management of radiation-induced urethral strictures.
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spelling pubmed-79698772021-03-19 Current Management of Membranous Urethral Strictures Due to Radiation Waterloos, Marjan Martins, Francisco Verla, Wesley Kluth, Luis Alex Lumen, Nicolaas Front Surg Surgery Radiotherapy is a frequently used treatment for prostate cancer. It does not only causes the intended damage to cancer cells, but also affects healthy surrounding tissue. As a result radiation-induced urethral strictures occur in 2.2% of prostate cancer patients. Management of urethral strictures is challenging due to the presence of poor vascularized tissue for reconstruction and the proximity of the sphincter, which can impair the functional outcome. This review provides a literature overview of risk factors, diagnostics and management of radiation-induced urethral strictures. Frontiers Media S.A. 2021-03-04 /pmc/articles/PMC7969877/ /pubmed/33748181 http://dx.doi.org/10.3389/fsurg.2021.635060 Text en Copyright © 2021 Waterloos, Martins, Verla, Kluth and Lumen. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Waterloos, Marjan
Martins, Francisco
Verla, Wesley
Kluth, Luis Alex
Lumen, Nicolaas
Current Management of Membranous Urethral Strictures Due to Radiation
title Current Management of Membranous Urethral Strictures Due to Radiation
title_full Current Management of Membranous Urethral Strictures Due to Radiation
title_fullStr Current Management of Membranous Urethral Strictures Due to Radiation
title_full_unstemmed Current Management of Membranous Urethral Strictures Due to Radiation
title_short Current Management of Membranous Urethral Strictures Due to Radiation
title_sort current management of membranous urethral strictures due to radiation
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969877/
https://www.ncbi.nlm.nih.gov/pubmed/33748181
http://dx.doi.org/10.3389/fsurg.2021.635060
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