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Complement Activation in the Central Nervous System: A Biophysical Model for Immune Dysregulation in the Disease State

Complement, a feature of the innate immune system that targets pathogens for phagocytic clearance and promotes inflammation, is tightly regulated to prevent damage to host tissue. This regulation is paramount in the central nervous system (CNS) since complement proteins degrade neuronal synapses dur...

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Detalles Bibliográficos
Autores principales: Peoples, Nicholas, Strang, Candace
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969890/
https://www.ncbi.nlm.nih.gov/pubmed/33746710
http://dx.doi.org/10.3389/fnmol.2021.620090

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