Cargando…

Effect of memantine, an anti-Alzheimer’s drug, on rodent microglial cells in vitro

The pathophysiology of Alzheimer’s disease (AD) is related to neuroinflammatory responses mediated by microglia. Memantine, an antagonist of N-methyl-d-aspartate (NMDA) receptors used as an anti-Alzheimer’s drug, protects from neuronal death accompanied by suppression of proliferation and activation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Murakawa-Hirachi, Toru, Mizoguchi, Yoshito, Ohgidani, Masahiro, Haraguchi, Yoshinori, Monji, Akira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969939/ https://www.ncbi.nlm.nih.gov/pubmed/33731780 http://dx.doi.org/10.1038/s41598-021-85625-4

Ejemplares similares

Microglial CD206 Gene Has Potential as a State Marker of Bipolar Disorder
por: Ohgidani, Masahiro, et al.
Publicado: (2017)

Donepezil suppresses intracellular Ca(2+) mobilization through the PI3K pathway in rodent microglia
por: Haraguchi, Yoshinori, et al.
Publicado: (2017)

Deep Vein Thrombosis after Lithium Toxicity: A Report of Two Cases and Literature Review
por: Sogawa, Rintaro, et al.
Publicado: (2021)

Microglial Intracellular Ca(2+) Signaling in Synaptic Development and its Alterations in Neurodevelopmental Disorders
por: Mizoguchi, Yoshito, et al.
Publicado: (2017)

Serum oxytocin correlated with later logical memory in older Japanese women: A 7-year follow-up study
por: Kunitake, Yutaka, et al.
Publicado: (2022)

Microglial intracellular Ca(2+) signaling as a target of antipsychotic actions for the treatment of schizophrenia
por: Mizoguchi, Yoshito, et al.
Publicado: (2014)

Improvement Of Frontal Lobe Dysfunction And White Matter Integrity By rTMS In Treatment-Resistant Depression
por: Tateishi, Hiroshi, et al.
Publicado: (2019)

Association Between sTREM2, an Immune Biomarker of Microglial Activation, and Aging-Related Brain Volume Changes in Community-Dwelling Older Adults: A 7-Year Follow-Up Study
por: Orihashi, Ryuzo, et al.
Publicado: (2021)

Hyperbaric Oxygen Therapy for Carbon Monoxide-Induced Delayed Neuropsychiatric Sequelae: Case Report of Two Cases and Relevant Literature Review
por: Monji, Akira, et al.
Publicado: (2021)

Is the Therapeutic Mechanism of Repetitive Transcranial Magnetic Stimulation in Cognitive Dysfunctions of Depression Related to the Neuroinflammatory Processes in Depression?
por: Tateishi, Hiroshi, et al.
Publicado: (2022)

Basic Study of Drug-Drug Interaction between Memantine and the Traditional Japanese Kampo Medicine Yokukansan
por: Matsumoto, Takashi, et al.
Publicado: (2018)

Update on the use of memantine in Alzheimer’s disease
por: van Marum, Robert J
Publicado: (2009)

Lower brain-derived neurotrophic factor levels are associated with age-related memory impairment in community-dwelling older adults: the Sefuri study
por: Mizoguchi, Yoshito, et al.
Publicado: (2020)

Association between cortisol and aging-related hippocampus volume changes in community-dwelling older adults: a 7-year follow-up study
por: Orihashi, Ryuzo, et al.
Publicado: (2022)

Memantine loaded PLGA PEGylated nanoparticles for Alzheimer’s disease: in vitro and in vivo characterization
por: Sánchez-López, Elena, et al.
Publicado: (2018)

Memantine Derivatives as Multitarget Agents in Alzheimer’s Disease
por: Marotta, Giambattista, et al.
Publicado: (2020)

Preliminary analysis of hippocampus synaptic apoptosis and microglial phagocytosis induced by severe restraint stress
por: Enomoto, Shingo, et al.
Publicado: (2022)

Oxytocin and elderly MRI-based hippocampus and amygdala volume: a 7-year follow-up study
por: Orihashi, Ryuzo, et al.
Publicado: (2020)

Correlation between Post-Acute Electroconvulsive Therapy Alpha-Band Spectrum Power Increase and Improvement of Psychiatric Symptoms
por: Iwanaga, Hideyuki, et al.
Publicado: (2021)

Memantine: efficacy and safety in mild-to-severe Alzheimer’s disease
por: Tampi, Rajesh R, et al.
Publicado: (2007)

Therapy of addition for Alzheimer's Disease: combination with galantamine and memantine
por: Zarra, Julio, et al.
Publicado: (2010)

Memantine-induced Myoclonus in a Patient with Alzheimer Disease
por: Murgai, Aditya A., et al.
Publicado: (2015)

Memantine prodrug as a new agent for Alzheimer’s Disease
por: Sestito, Simona, et al.
Publicado: (2019)

Development of a delirium predictive model for adult trauma patients in an emergency and critical care center: a retrospective study
por: Matsuoka, Ayaka, et al.
Publicado: (2021)

Ameliorative effects of Fingolimod (FTY720) on microglial activation and psychosis-related behavior in short term cuprizone exposed mice
por: Li, Siyao, et al.
Publicado: (2023)

Low-Grade Inflammation Is Associated with Apathy Indirectly via Deep White Matter Lesions in Community-Dwelling Older Adults: The Sefuri Study
por: Yao, Hiroshi, et al.
Publicado: (2019)

Memantine and Cholinesterase Inhibitors: Complementary Mechanisms in the Treatment of Alzheimer’s Disease
por: Parsons, Chris G., et al.
Publicado: (2013)

Memantine Attenuates Alzheimer’s Disease-Like Pathology and Cognitive Impairment
por: Wang, Xiaochuan, et al.
Publicado: (2015)

Galantamine-memantine combination superior to donepezil-memantine combination in Alzheimer’s disease: critical dissection with an emphasis on kynurenic acid and mismatch negativity
por: Koola, Maju Mathew, et al.
Publicado: (2018)

Serum soluble triggering receptor expressed on myeloid cells‐2 was not altered by rTMS in patients with treatment‐resistant depression
por: Tateishi, Hiroshi, et al.
Publicado: (2023)

Cost-effectiveness analysis of memantine for moderate-to-severe Alzheimer’s disease in the Netherlands
por: Hoogveldt, Bart, et al.
Publicado: (2011)

Memantine Monotherapy for Alzheimer’s Disease: A Systematic Review and Meta-Analysis
por: Matsunaga, Shinji, et al.
Publicado: (2015)

Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer’s disease
por: Sobue, Akira, et al.
Publicado: (2021)

Pharmacodynamics of Memantine: An Update
por: Rammes, G, et al.
Publicado: (2008)

Pharmacokinetic Drug-Drug Interaction and Responsible Mechanism between Memantine and Cimetidine
por: Choi, Young A., et al.
Publicado: (2018)

Persistent treatment with cholinesterase inhibitors and/or memantine slows clinical progression of Alzheimer disease
por: Rountree, Susan D, et al.
Publicado: (2009)

Memantine and cholinesterase inhibitor combination therapy for Alzheimer's disease: a systematic review
por: Farrimond, Lucy E, et al.
Publicado: (2012)

The effects of memantine on behavioral disturbances in patients with Alzheimer’s disease: a meta-analysis
por: Kishi, Taro, et al.
Publicado: (2017)

Minocycline, a microglial inhibitor, reduces ‘honey trap’ risk in human economic exchange
por: Watabe, Motoki, et al.
Publicado: (2013)

Neuroinflammation in Alzheimer’s disease: microglial signature and their relevance to disease
por: Sobue, Akira, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_56lh60f6u930m058of7u3046gp