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Splicing reprogramming of TRAIL/DISC-components sensitizes lung cancer cells to TRAIL-mediated apoptosis

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selective killing of cancer cells underlines its anticancer potential. However, poor tolerability and resistance underscores the need to identify cancer-selective TRAIL-sensitizing agents. Apigenin, a dietary flavonoid, sensitizes lung...

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Detalles Bibliográficos
Autores principales: Voss, Oliver H., Arango, Daniel, Tossey, Justin C., Villalona Calero, Miguel A., Doseff, Andrea I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7969956/
https://www.ncbi.nlm.nih.gov/pubmed/33731677
http://dx.doi.org/10.1038/s41419-021-03567-1